In vitro and in vivo studies of androst-4-ene-3,6,17-trione in horses by gas chromatography-mass spectrometry

This paper describes the application of gas chromatography–mass spectrometry (GC‐MS) for in vitro and in vivo studies of 6‐OXO in horses, with a special aim to identify the most appropriate target metabolite to be monitored for controlling the administration of 6‐OXO in racehorses. In vitro studies...

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Bibliographic Details
Published in:	Biomedical chromatography Vol. 24; no. 7; pp. 744 - 751
Main Authors:	Leung, Gary N. W., Tang, Francis P. W., Wan, Terence S. M., Wong, Colton H. F., Lam, Kenneth K. H., Stewart, Brian D.
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 01-07-2010
Subjects:	17-trione 6-OXO Anabolic Agents - analysis Anabolic Agents - metabolism Anabolic Agents - urine androst-4-ene-3 Androstenes - analysis Androstenes - metabolism Androstenes - urine androst‐4‐ene‐3,6,17‐trione Animals Doping in Sports gas chromatography-mass spectrometry (GC-MS) Gas Chromatography-Mass Spectrometry - methods horse Horses - urine metabolism Microsomes, Liver - chemistry Microsomes, Liver - metabolism
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