Gastric emptying of carbohydrate--medium chain triglyceride suspensions at rest

• Published in: International journal of sports medicine Vol. 13; no. 8; p. 581
• Main Authors: Beckers, E J, Jeukendrup, A E, Brouns, F, Wagenmakers, A J, Saris, W H
• Format: Journal Article
• Language: English
• Published: Germany 01-11-1992
• Subjects: Adult; Dietary Carbohydrates - pharmacology; Dietary Fats - pharmacology; Exercise - physiology; Gastric Emptying - drug effects; Gastric Emptying - physiology; Humans; Male; Osmolar Concentration; Time Factors; Triglycerides - pharmacology
• ISSN: 0172-4622
• DOI: 10.1055/s-2007-1024569

Nine male volunteers participated in 4 gastric emptying (GE) tests of liquid equicaloric mixtures of CHO (maltodextrins) and MCT of the following composition (% CHO-% MCT): Drink (Dr) 1:70%-30%, Dr2: 80%-20%, Dr3: 90%-10%, Dr4: 100%-0%. GE was measured at rest for 90 min according to the modified double sampling technique. GE rate, expressed as t1/2 (SEM), was 23 (2.3), 24 (1.6), 27 (2.2) and 36 (2.9) min, respectively, from drink 1 to drink 4. Statistical analysis showed that all MCT containing drinks emptied faster than the 100% CHO drink. Two mechanisms may explain this observation: 1) the CHO content and osmolality increases from Dr 1 to Dr 4 (both are regulators of GE); 2) MCT may not inhibit GE as common fat does, due to a better water solubility and absorption in the small intestine, resulting in a decreased duodenal-gastric feedback.