Radiotherapy on hidradenocarcinoma

• Published in: North American journal of medical sciences Vol. 3; no. 1; pp. 43 - 45
• Main Authors: Lalya, Issam, Hadadi, Khalid, Tazi, El Mehdi, Lalya, Ilham, Bazine, Amine, Andaloussy, Khalid, Elmarjany, Mohamed, Sifat, Hassan, Hassouni, Khalid, Kebdani, Tayeb, Mansouri, Hamid, Benjaafar, Noureddine, Elgueddari, Brahim Khalil
• Format: Journal Article
• Language: English
• Published: India Medknow Publications & Media Pvt Ltd 01-01-2011
• Subjects: Case Report; recurrence; megavoltage external beam radiotherapy; Hidradenocarcinoma; sweat-gland; rare; surgery
• ISSN: 1947-2714; 2250-1541; 1947-2714
• DOI: 10.4297/najms.2011.343

Clear cell Hidradenocarcinoma is a rare carcinoma arising from sweat glands. It is an aggressive tumor that most metastasizes to regional lymph nodes and distant viscera; surgery with safe margins is the mainstay of treatment.
We report a case of 68-year-old woman who presented with an invasive clear cell hidradenocarcinoma situated in the left parotid area which recurred 5 months after surgery, this recurrence was managed successfully by high-dose irradiation of the tumor bed (66 Gy) and regional lymphatic chains (50 Gy), after a follow-up of more than 15 months, the patient is in good local control without significant toxicity.
POST OPERATIVE RADIOTHERAPY ALLOWS BETTER LOCAL CONTROL AND SHOULD BE MANDATORY WHEN HISTOLOGICAL FEATURES PREDICTIVE OF RECURRENCE ARE PRESENT: positive margins, histology poorly differentiated, perineural invasion, vascular and lymphatic invasion, lymph node involvement, and extracapsular spread.