The effect of cervical/vaginal secretions on measurements of lecithin/sphingomyelin ratio and optical density at 650 nm

The effect of cervical/vaginal secretions on measurements of lecithin/sphingomyelin ratio and optical density at 650 nm

Free-flowing amniotic fluid collected vaginally can be used in a reliable way for determination of fetal pulmonary maturity. Lavaging the vaginal/cervical area with sterile saline and examining the lavage fluid for lecithin/sphingomyelin (L/S) spots showed no detectable spots in the supernatants (on...

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Bibliographic Details
Published in:American journal of obstetrics and gynecology Vol. 139; no. 2; p. 214
Main Authors: Sbarra, A J, Blake, G, Cetrulo, C L, Selvaraj, R J, Herschel, M J, Delise, C, Kennedy, J L, Mitchell, Jr, G W
Format: Journal Article
Language:English
Published: United States 15-01-1981
Subjects:
Amniotic Fluid - analysis
Cervix Mucus - analysis
Female
Fetal Membranes, Premature Rupture - diagnosis
Fetal Organ Maturity
Humans
Phosphatidylcholines - analysis
Pregnancy
Sodium Chloride - pharmacology
Spectrophotometry - methods
Sphingomyelins - analysis
Therapeutic Irrigation
Vagina - metabolism
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Summary:Free-flowing amniotic fluid collected vaginally can be used in a reliable way for determination of fetal pulmonary maturity. Lavaging the vaginal/cervical area with sterile saline and examining the lavage fluid for lecithin/sphingomyelin (L/S) spots showed no detectable spots in the supernatants (one exception) and barely detectable L/S spots in the sediment. Vaginal-cervical saline-wash fluids did not affect fluid L/S ratios. Lavaging the vaginal-cervical area with abdominal amniotic fluid did not affect the L/S ratio of the original amniotic fluid.
ISSN:0002-9378
DOI:10.1016/0002-9378(81)90449-X