Cytogenetic analysis of SV40-transformed human breast epithelial cells

The SV40-transformed breast epithelial cell lines established by Chang et al. [1] were shown to be hypotetraploid and characterized by six chromosome markers: M1 i(1q), M2 del(1)(q21), M3 i(6p), M4 del(1)(q11), M5 t(8p;12q), and M6 dir dup(11)(p12 leads to pter). The presence of common chromosome ma...

Full description

Saved in:

Bibliographic Details
Published in:	Cancer genetics and cytogenetics Vol. 8; no. 3; p. 213
Main Authors:	Rodgers, C S, Hill, S M, Hultén, M A, Chang, S E, Keen, J, Taylor-Papadimitriou, J
Format:	Journal Article
Language:	English
Published:	United States 01-03-1983
Subjects:	Breast Cell Line Cell Transformation, Viral Chromosome Aberrations Epithelial Cells Fibroblasts - cytology Humans Polyploidy Simian virus 40
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The SV40-transformed breast epithelial cell lines established by Chang et al. [1] were shown to be hypotetraploid and characterized by six chromosome markers: M1 i(1q), M2 del(1)(q21), M3 i(6p), M4 del(1)(q11), M5 t(8p;12q), and M6 dir dup(11)(p12 leads to pter). The presence of common chromosome markers indicates that these cell lines are probably derived from the same original transformed cell.
ISSN:	0165-4608
DOI:	10.1016/0165-4608(83)90137-1