Nocardia brain abscess mimicking brain tumour in immunocompetent patients: report of two cases and review of the literature

Nocardia brain abscess is a rare intracranial lesion and has been reported in immunocompromised patients. An optimal treatment approach has not been established. However, early diagnosis and appropriate antimicrobial therapy are very important factors for a good outcome. We report two unusual cases...

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Published in:Acta neurochirurgica Vol. 146; no. 4; pp. 411 - 414
Main Authors: Menkü, A, Kurtsoy, A, Tucer, B, Yildiz, O, Akdemir, H
Format: Journal Article
Language:English
Published: Austria Springer Nature B.V 01-04-2004
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Abstract Nocardia brain abscess is a rare intracranial lesion and has been reported in immunocompromised patients. An optimal treatment approach has not been established. However, early diagnosis and appropriate antimicrobial therapy are very important factors for a good outcome. We report two unusual cases of Nocardia brain abscess simulating brain tumour in immunocompetent patients. One of the cases was presumed to be a primary brain tumour and the other a metastatic brain tumour. They underwent surgical gross total resection. After Nocardia asteroides was seen on Gram's stain and subsequently identified by culture, appropriate antibiotic therapy was initiated.
AbstractList Nocardia brain abscess is a rare intracranial lesion and has been reported in immunocompromised patients. An optimal treatment approach has not been established. However, early diagnosis and appropriate antimicrobial therapy are very important factors for a good outcome. We report two unusual cases of Nocardia brain abscess simulating brain tumour in immunocompetent patients. One of the cases was presumed to be a primary brain tumour and the other a metastatic brain tumour. They underwent surgical gross total resection. After Nocardia asteroides was seen on Gram's stain and subsequently identified by culture, appropriate antibiotic therapy was initiated.
Nocardia brain abscess is a rare intracranial lesion and has been reported in immunocompromised patients. An optimal treatment approach has not been established. However, early diagnosis and appropriate antimicrobial therapy are very important factors for a good outcome. We report two unusual cases of Nocardia brain abscess simulating brain tumour in immunocompetent patients. One of the cases was presumed to be a primary brain tumour and the other a metastatic brain tumour. They underwent surgical gross total resection. After Nocardia asteroides was seen on Gram's stain and subsequently identified by culture, appropriate antibiotic therapy was initiated.[PUBLICATION ABSTRACT]
Author Tucer, B
Kurtsoy, A
Yildiz, O
Menkü, A
Akdemir, H
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  surname: Menkü
  fullname: Menkü, A
  email: menkua@erciyes.edu.tr
  organization: Department of Neurosurgery, Erciyes University School of Medicine, Kayseri, Turkey. menkua@erciyes.edu.tr
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  surname: Yildiz
  fullname: Yildiz, O
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  fullname: Akdemir, H
BackLink https://www.ncbi.nlm.nih.gov/pubmed/15057538$$D View this record in MEDLINE/PubMed
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SubjectTerms Adolescent
Brain Abscess - diagnosis
Brain Abscess - surgery
Brain cancer
Brain Neoplasms - diagnosis
Diagnosis, Differential
Humans
Immunocompetence
Infections
Male
Middle Aged
Neuronavigation
Nocardia asteroides
Nocardia Infections - diagnosis
Nocardia Infections - surgery
Title Nocardia brain abscess mimicking brain tumour in immunocompetent patients: report of two cases and review of the literature
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