Nocardia brain abscess mimicking brain tumour in immunocompetent patients: report of two cases and review of the literature

Nocardia brain abscess is a rare intracranial lesion and has been reported in immunocompromised patients. An optimal treatment approach has not been established. However, early diagnosis and appropriate antimicrobial therapy are very important factors for a good outcome. We report two unusual cases...

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Bibliographic Details
Published in:	Acta neurochirurgica Vol. 146; no. 4; pp. 411 - 414
Main Authors:	Menkü, A, Kurtsoy, A, Tucer, B, Yildiz, O, Akdemir, H
Format:	Journal Article
Language:	English
Published:	Austria Springer Nature B.V 01-04-2004
Subjects:	Adolescent Brain Abscess - diagnosis Brain Abscess - surgery Brain cancer Brain Neoplasms - diagnosis Diagnosis, Differential Humans Immunocompetence Infections Male Middle Aged Neuronavigation Nocardia asteroides Nocardia Infections - diagnosis Nocardia Infections - surgery
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Summary:	Nocardia brain abscess is a rare intracranial lesion and has been reported in immunocompromised patients. An optimal treatment approach has not been established. However, early diagnosis and appropriate antimicrobial therapy are very important factors for a good outcome. We report two unusual cases of Nocardia brain abscess simulating brain tumour in immunocompetent patients. One of the cases was presumed to be a primary brain tumour and the other a metastatic brain tumour. They underwent surgical gross total resection. After Nocardia asteroides was seen on Gram's stain and subsequently identified by culture, appropriate antibiotic therapy was initiated.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0001-6268 0942-0940
DOI:	10.1007/s00701-004-0215-6