Experience with 5% ethanolamine oleate for sclerotherapy of oral vascular anomalies: A cohort of 15 consecutive patients

• Published in: Journal of cranio-maxillo-facial surgery Vol. 47; no. 1; pp. 106 - 111
• Main Authors: Kato, Camila de Nazaré Alves de Oliveira, Ribeiro, Michel Campos, do Amaral, Márcio Bruno Figueiredo, Grossmann, Soraya de Mattos Camargo, de Aguiar, Maria Cássia Ferreira, Mesquita, Ricardo Alves
• Format: Journal Article
• Language: English
• Published: Scotland Elsevier Ltd 01-01-2019
• Subjects: Dentistry; Ethanolamine; Sclerotherapy; Varicose vein; Vascular malformation; Varicose vein; Vascular malformation; Ethanolamine; Sclerotherapy
• ISSN: 1010-5182; 1878-4119
• DOI: 10.1016/j.jcms.2018.11.009

To describe the effectiveness and safety of a sclerotherapy protocol with 5% ethanolamine oleate (EO) at 0.1 mL/3 mm for oral vascular anomalies (OVAs). Our hypothesis is that EO applied at a concentration of 5% may decrease the number of sessions necessary for clinical healing.
We describe a cohort of 15 consecutive patients. OVAs <20 mm were included. Clinical data of the OVAs were collected. Descriptive and bivariate statistical analyses were performed.
Fifteen of the 19 OVAs were varicosities and the lower lip was the most affected site (n = 7). The median size was 6 mm, and one session was required in 89.5% of cases for clinical healing within 28 days. The pain/burning score was low (<2) for most lesions (63.1%) and the degree of satisfaction was high (>8) for all OVAs. The number of applications, final volume of drug and time to resolution differed significantly according to the size of the anomaly.
The protocol with 5% EO was shown to be effective and safe to treat OVAs <20 mm, and with a decrease in the number of sessions, volume and time to resolution, without complications and with high patient satisfaction.