Oxidative stress and the pathogenesis of heart failure

Oxidative stress and the pathogenesis of heart failure

There is strong evidence for an adverse role of oxidative stress in CHF in both animals and humans. Antioxidant supplement have been very effective in the treatment of animal paradigms; however, the data for the possible benefits of treatment for patients with CHF is either retrospective or inferent...

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Bibliographic Details
Published in:Cardiology clinics Vol. 16; no. 4; p. 665
Main Authors: Ball, A M, Sole, M J
Format: Journal Article
Language:English
Published: Netherlands 01-11-1998
Subjects:
Animals
Antioxidants
Heart Failure - etiology
Humans
Myocardium - metabolism
Oxidative Stress
Reactive Oxygen Species
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Summary:There is strong evidence for an adverse role of oxidative stress in CHF in both animals and humans. Antioxidant supplement have been very effective in the treatment of animal paradigms; however, the data for the possible benefits of treatment for patients with CHF is either retrospective or inferential. Such information is important and should be the subject of prospective randomized trials.
ISSN:0733-8651
DOI:10.1016/S0733-8651(05)70043-6