Potential ultrasonic anatomical markers of obstructive sleep apnoea–hypopnoea syndrome

• Published in: Clinical radiology Vol. 78; no. 2; pp. e137 - e142
• Main Authors: Lun, H.-M., Liu, R.-C., Hu, Q., Liu, Y.-L., Wei, L.-S., Wu, D., Wang, F., Zhu, S.-Y.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-02-2023
• Subjects: Humans; Polysomnography; Sleep Apnea Syndromes; Sleep Apnea, Obstructive - diagnostic imaging; Ultrasonics; Ultrasonography
• ISSN: 0009-9260; 1365-229X
• DOI: 10.1016/j.crad.2022.09.128

To investigate the potential value of ultrasonography in evaluating the pathophysiology of obstructive sleep apnoea–hypopnoea syndrome (OSAHS) by assessing the correlation of critical ultrasonic anatomical characteristics of the oropharynx with the severity of OSAHS.
One hundred and seventy-one patients with suspected OSAHS underwent oropharyngeal sonographic examination and overnight polysomnography. Ultrasonic measurement was compared with the apnoea–hypopnoea index (AHI) and other parameters. An ordinal logistic regression model was used to identify potential ultrasonic anatomical markers for OSAHS.
The AHI was significantly correlated with lingual height (r=0.40, p<0.01), maximal width of the tongue (r=0.35, p<0.01), and distance from the symphysis of the mandible to the hyoid bone (M-HB) (r=0.24, p<0.01). A positive relationship between Friedman tongue position (FTP) grades and lingual height (r=0.24, p<0.01), between FTP grades and maximal width of the tongue (r=0.23, p<0.01), and between FTP grades and width of tongue base (TB; r=0.17, p<0.05) was found. Multivariate models adjusted for sex, age, and body mass index (BMI) revealed that lingual height (95% confidence interval [CI]: 1.04–1.24; p=0.004) is independently associated with a higher risk for the severity of OSAHS.
Ultrasonography may be a potential imaging method for providing additional useful information about the correlation between ultrasound findings and the severity of OSAHS. Lingual height could be considered an ultrasonic anatomical marker for determining the severity of OSAHS patients independent of age, sex, and BMI.
•Quantitative ultrasound measurements of oropharynx are technically feasible.•A positive relationship between FTP grades and ultrasonic measurements was found.•Lingual height can be used as anatomic marker for determining the severity of OSAHS.