Acquired renal cystic disease and adenocarcinoma following renal transplantation--a current urologic perspective

Two patients treated with chronic dialysis and renal transplantation developed acute hemorrhage from a native kidney. Bilateral native nephrectomy demonstrated acquired cystic disease and adenocarcinoma in each of the four kidneys. The etiology of acquired cystic kidney disease (ACKD) is unclear and...

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Bibliographic Details
Published in:	Urologia internationalis Vol. 60; no. 2; p. 108
Main Authors:	Sant, G R, Ucci, Jr, A A
Format:	Journal Article
Language:	English
Published:	Switzerland 01-01-1998
Subjects:	Angiography Carcinoma, Renal Cell - etiology Carcinoma, Renal Cell - pathology Diagnosis, Differential Follow-Up Studies Humans Kidney Diseases, Cystic - etiology Kidney Diseases, Cystic - pathology Kidney Failure, Chronic - therapy Kidney Neoplasms - etiology Kidney Neoplasms - pathology Kidney Transplantation - adverse effects Male Middle Aged Renal Dialysis Tomography, X-Ray Computed
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Summary:	Two patients treated with chronic dialysis and renal transplantation developed acute hemorrhage from a native kidney. Bilateral native nephrectomy demonstrated acquired cystic disease and adenocarcinoma in each of the four kidneys. The etiology of acquired cystic kidney disease (ACKD) is unclear and its incidence increases with the duration of dialysis. ACKD patients have a propensity to develop adenomas and adenocarcinomas. The increased incidence of renal neoplasms in ACKD patients warrants careful radiologic monitoring of native end-stage kidneys in selected patients.
ISSN:	0042-1138
DOI:	10.1159/000030222