Exploiting Anatomical Landmarks for Efficient In Vivo CLEM

Established protocols for correlating intravital microscopy with electron microscopy remain cumbersome and mostly rely on a combination of artificial fiducials with anatomical landmarks. A recent study describes a new workflow, achieving label-free 3D correlative light and electron microscopy in the...

Full description

Saved in:
Bibliographic Details
Published in:Trends in biochemical sciences (Amsterdam. Regular ed.) Vol. 43; no. 10; pp. 744 - 747
Main Author: Goetz, Jacky G.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01-10-2018
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Established protocols for correlating intravital microscopy with electron microscopy remain cumbersome and mostly rely on a combination of artificial fiducials with anatomical landmarks. A recent study describes a new workflow, achieving label-free 3D correlative light and electron microscopy in the mouse brain.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0968-0004
1362-4326
DOI:10.1016/j.tibs.2018.08.003