Dry Eye Assessment in Patients With Vitamin D Deficiency
OBJECTIVES:The aim of this study was to evaluate tear film function in patients with vitamin D deficiency. METHODS:In a single center, 60 eyes of 30 patients with vitamin D deficiency (group 1), and 60 eyes of 30 healthy individuals (group 2) were evaluated using the Ocular Surface Disease Index (OS...
Saved in:
| Published in: | Eye & contact lens Vol. 44 Suppl 1; no. 1; pp. S62 - S65 |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
Contact Lens Association of Ophthalmologists, Inc
01-09-2018
|
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | OBJECTIVES:The aim of this study was to evaluate tear film function in patients with vitamin D deficiency.
METHODS:In a single center, 60 eyes of 30 patients with vitamin D deficiency (group 1), and 60 eyes of 30 healthy individuals (group 2) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear break-up time (TBUT), scoring of ocular surface fluorescein staining using a modified Oxford scale, and tear osmolarity.
RESULTS:Tear osmolarity values, OSDI, and Oxford scale scores were significantly higher in group 1 (309±9 mOsm/L, 35.78±21.44 and 1.3±0.9, respectively) compared with group 2 (295±10 mOsm/L, 18.69±17.21 and 0.4±0.8, respectively) (P<0.001 for all). Schirmer I test and TBUT results in group 1 (8.5±3.7 mm and 8.7±0.6 sec, respectively) were significantly lower compared with group 2 (16.6±2.4 and 18.1±0.5, respectively) (P<0.001 for all).
CONCLUSIONS:This study demonstrates that vitamin D deficiency is associated with tear hyperosmolarity and tear film dysfunction. Patients with vitamin D deficiency may be prone to dry eye. |
|---|---|
| AbstractList | OBJECTIVESThe aim of this study was to evaluate tear film function in patients with vitamin D deficiency.METHODSIn a single center, 60 eyes of 30 patients with vitamin D deficiency (group 1), and 60 eyes of 30 healthy individuals (group 2) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear break-up time (TBUT), scoring of ocular surface fluorescein staining using a modified Oxford scale, and tear osmolarity.RESULTSTear osmolarity values, OSDI, and Oxford scale scores were significantly higher in group 1 (309±9 mOsm/L, 35.78±21.44 and 1.3±0.9, respectively) compared with group 2 (295±10 mOsm/L, 18.69±17.21 and 0.4±0.8, respectively) (P<0.001 for all). Schirmer I test and TBUT results in group 1 (8.5±3.7 mm and 8.7±0.6 sec, respectively) were significantly lower compared with group 2 (16.6±2.4 and 18.1±0.5, respectively) (P<0.001 for all).CONCLUSIONSThis study demonstrates that vitamin D deficiency is associated with tear hyperosmolarity and tear film dysfunction. Patients with vitamin D deficiency may be prone to dry eye. The aim of this study was to evaluate tear film function in patients with vitamin D deficiency. In a single center, 60 eyes of 30 patients with vitamin D deficiency (group 1), and 60 eyes of 30 healthy individuals (group 2) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear break-up time (TBUT), scoring of ocular surface fluorescein staining using a modified Oxford scale, and tear osmolarity. Tear osmolarity values, OSDI, and Oxford scale scores were significantly higher in group 1 (309±9 mOsm/L, 35.78±21.44 and 1.3±0.9, respectively) compared with group 2 (295±10 mOsm/L, 18.69±17.21 and 0.4±0.8, respectively) (P<0.001 for all). Schirmer I test and TBUT results in group 1 (8.5±3.7 mm and 8.7±0.6 sec, respectively) were significantly lower compared with group 2 (16.6±2.4 and 18.1±0.5, respectively) (P<0.001 for all). This study demonstrates that vitamin D deficiency is associated with tear hyperosmolarity and tear film dysfunction. Patients with vitamin D deficiency may be prone to dry eye. Objectives: The aim of this study was to evaluate tear film function in patients with vitamin D deficiency. Methods: In a single center, 60 eyes of 30 patients with vitamin D deficiency (group 1), and 60 eyes of 30 healthy individuals (group 2) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear break-up time (TBUT), scoring of ocular surface fluorescein staining using a modified Oxford scale, and tear osmolarity. Results: Tear osmolarity values, OSDI, and Oxford scale scores were significantly higher in group 1 (309±9 mOsm/L, 35.78±21.44 and 1.3±0.9, respectively) compared with group 2 (295±10 mOsm/L, 18.69±17.21 and 0.4±0.8, respectively) ( P <0.001 for all). Schirmer I test and TBUT results in group 1 (8.5±3.7 mm and 8.7±0.6 sec, respectively) were significantly lower compared with group 2 (16.6±2.4 and 18.1±0.5, respectively) ( P <0.001 for all). Conclusions: This study demonstrates that vitamin D deficiency is associated with tear hyperosmolarity and tear film dysfunction. Patients with vitamin D deficiency may be prone to dry eye. OBJECTIVES:The aim of this study was to evaluate tear film function in patients with vitamin D deficiency. METHODS:In a single center, 60 eyes of 30 patients with vitamin D deficiency (group 1), and 60 eyes of 30 healthy individuals (group 2) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear break-up time (TBUT), scoring of ocular surface fluorescein staining using a modified Oxford scale, and tear osmolarity. RESULTS:Tear osmolarity values, OSDI, and Oxford scale scores were significantly higher in group 1 (309±9 mOsm/L, 35.78±21.44 and 1.3±0.9, respectively) compared with group 2 (295±10 mOsm/L, 18.69±17.21 and 0.4±0.8, respectively) (P<0.001 for all). Schirmer I test and TBUT results in group 1 (8.5±3.7 mm and 8.7±0.6 sec, respectively) were significantly lower compared with group 2 (16.6±2.4 and 18.1±0.5, respectively) (P<0.001 for all). CONCLUSIONS:This study demonstrates that vitamin D deficiency is associated with tear hyperosmolarity and tear film dysfunction. Patients with vitamin D deficiency may be prone to dry eye. |
| Author | Eliacik, Mustafa Demirci, Goktug Ozsutcu, Mustafa Olmuscelik, Oktay Aydin, Rukiye Karaman Erdur, Sevil Kocabora, Mehmet Selim |
| AuthorAffiliation | Departments of Ophthalmology (G.D., S.K.E., M.O., M.E., R.A., M.S.K.), and Internal Medicine (O.O.), Istanbul Medipol University, Istanbul, Turkey |
| AuthorAffiliation_xml | – name: Departments of Ophthalmology (G.D., S.K.E., M.O., M.E., R.A., M.S.K.), and Internal Medicine (O.O.), Istanbul Medipol University, Istanbul, Turkey |
| Author_xml | – sequence: 1 givenname: Goktug surname: Demirci fullname: Demirci, Goktug organization: Departments of Ophthalmology (G.D., S.K.E., M.O., M.E., R.A., M.S.K.), and Internal Medicine (O.O.), Istanbul Medipol University, Istanbul, Turkey – sequence: 2 givenname: Sevil surname: Karaman Erdur fullname: Karaman Erdur, Sevil – sequence: 3 givenname: Mustafa surname: Ozsutcu fullname: Ozsutcu, Mustafa – sequence: 4 givenname: Mustafa surname: Eliacik fullname: Eliacik, Mustafa – sequence: 5 givenname: Oktay surname: Olmuscelik fullname: Olmuscelik, Oktay – sequence: 6 givenname: Rukiye surname: Aydin fullname: Aydin, Rukiye – sequence: 7 givenname: Mehmet surname: Kocabora middlename: Selim fullname: Kocabora, Mehmet Selim |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27660921$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kMtLw0AQxhep2If-ByI5ekndd3aPpa1aKOjB123ZJBMazaPuJpT890Zai3hwLjPMfN838BujQVVXgNAlwVOCdXSzmq-n-HcxKk7QiAhOQ8rY2-A4UzJEY-_fMaaYaHKGhjSSEmtKRkgtXBcsOwhm3oP3JVRNkFfBo23yfvTBa95sgpe8sWW_XQQLyPKkvyTdOTrNbOHh4tAn6Pl2-TS_D9cPd6v5bB0mTEgRxkRJkAyLNOVaioxymQmbMCUwtkqxKONCKx7RVCUiySLGUw0y1lFMMKdWsAm63uduXf3Zgm9MmfsEisJWULfeECV0RAmnupfyvTRxtfcOMrN1eWldZwg238xMz8z8Zdbbrg4f2riE9Gj6gdQL1F6wq4sGnP8o2h04swFbNJv_s78A3j124Q |
| CitedBy_id | crossref_primary_10_1055_a_1990_8942 crossref_primary_10_3390_antiox10020190 crossref_primary_10_4103_IJO_IJO_2838_22 crossref_primary_10_1097_ICO_0000000000003400 crossref_primary_10_1152_ajpheart_00319_2017 crossref_primary_10_18231_j_ijceo_2024_002 crossref_primary_10_4142_jvs_22237 crossref_primary_10_7759_cureus_15159 crossref_primary_10_1016_j_jtos_2022_08_005 crossref_primary_10_18410_jebmh_2019_672 crossref_primary_10_4103_mmj_mmj_245_21 crossref_primary_10_1097_j_jcrs_0000000000000771 crossref_primary_10_1055_s_0043_1762915 crossref_primary_10_1080_08820538_2017_1358752 crossref_primary_10_1016_j_yaoo_2024_04_004 crossref_primary_10_12677_ACM_2024_141111 crossref_primary_10_3390_ijms24021488 crossref_primary_10_3390_ijms23084226 crossref_primary_10_4103_ijabmr_ijabmr_637_22 crossref_primary_10_1097_ICO_0000000000003555 crossref_primary_10_1080_08164622_2022_2033601 crossref_primary_10_3390_nu14112353 crossref_primary_10_1111_aos_14470 crossref_primary_10_1007_s10792_020_01336_1 crossref_primary_10_3390_ijms24021458 crossref_primary_10_1016_j_jtos_2024_01_009 |
| Cites_doi | 10.1038/eye.2015.96 10.1016/S2213-8587(13)70165-7 10.1167/iovs.11-7605 10.1097/01.ICL.0000162759.79740.46 10.1016/S1542-0124(12)70081-2 10.1111/1756-185X.12727 10.1016/j.autrev.2010.02.011 10.1097/ICO.0000000000000089 10.1080/03009749950154266 10.1111/j.1755-3768.2011.02196.x 10.1001/archophthalmol.2011.364 10.1016/j.exer.2015.02.019 10.1136/bmj.g1903 10.1016/j.jtos.2013.07.003 10.1097/00003226-200310000-00008 10.1007/978-1-4615-0717-8_62 10.1016/j.diabres.2014.12.008 10.3109/02713683.2012.688235 |
| ContentType | Journal Article |
| Copyright | 2018 Contact Lens Association of Ophthalmologists, Inc. |
| Copyright_xml | – notice: 2018 Contact Lens Association of Ophthalmologists, Inc. |
| DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
| DOI | 10.1097/ICL.0000000000000325 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE CrossRef |
| Database_xml | – sequence: 1 dbid: ECM name: MEDLINE url: https://search.ebscohost.com/login.aspx?direct=true&db=cmedm&site=ehost-live sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1542-233X |
| EndPage | S65 |
| ExternalDocumentID | 10_1097_ICL_0000000000000325 27660921 10.1097/ICL.0000000000000325 |
| Genre | Journal Article Observational Study |
| GroupedDBID | - .Z2 0R 2V- 5GY 5VS AAPBV AARTV ABBUW ABXRP ABXVJ ABZAD ACDDN ACEWG ACGFS ACNCT ACWDW ACWRI ACXNZ ADFPA ADNKB AE3 AHULI AHVBC AJIOK AJNYG ALMA_UNASSIGNED_HOLDINGS AMJPA ASCII AWKKM BQLVK C45 CS3 DUNZO E.X EBS EJD EX3 F5P FL- H0 H0~ HZ IN IN~ JK3 JK8 K8S KD2 L-C N~M O9- OCUKA ODA OHASI OLW OPUJH ORVUJ OUVQU OVD OVDNE OXXIT R58 RIG RLZ RSW S4R S4S UCJ V2I WOQ WOW X3V X3W Z2 --- 0R~ 53G AAAAV AAHPQ AAIQE AASCR ABASU ABDIG ABJNI ABVCZ ACGFO ACILI ACXJB ADGGA ADHPY AEETU AFDTB AHQNM AINUH AJNWD AJZMW ALMTX AMKUR AMNEI AOHHW BS7 CGR CUY CVF DIWNM ECM EEVPB EIF FCALG GNXGY GQDEL HLJTE HZ~ IKREB IPNFZ NPM TEORI TSPGW W3M ZB8 ZZMQN AAYXX CITATION 7X8 |
| ID | FETCH-LOGICAL-c3565-b186e6305dd4965f246f5ac38500a8837f4598472d8c5cf734d9e6b97b1042a53 |
| ISSN | 1542-2321 |
| IngestDate | Tue Aug 27 04:54:00 EDT 2024 Fri Aug 23 01:35:52 EDT 2024 Wed Oct 16 00:59:53 EDT 2024 Thu Aug 13 19:52:28 EDT 2020 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c3565-b186e6305dd4965f246f5ac38500a8837f4598472d8c5cf734d9e6b97b1042a53 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Undefined-1 ObjectType-Feature-3 content type line 23 |
| PMID | 27660921 |
| PQID | 1859721429 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_1859721429 crossref_primary_10_1097_ICL_0000000000000325 pubmed_primary_27660921 wolterskluwer_health_10_1097_ICL_0000000000000325 |
| ProviderPackageCode | ACEWG L-C C45 .Z2 AARTV ADFPA ASCII AWKKM ODA ABZAD ABBUW JK3 OUVQU ADNKB JK8 H0~ ORVUJ X3V OLW X3W ACDDN ACWRI OHASI AHVBC AJNYG ABXRP FL- K8S AJIOK OPUJH V2I E.X OCUKA S4R ACXNZ S4S DUNZO OVDNE AMJPA ABXVJ IN~ KD2 OXXIT ACWDW OVD AHULI |
| PublicationCentury | 2000 |
| PublicationDate | 2018-September |
| PublicationDateYYYYMMDD | 2018-09-01 |
| PublicationDate_xml | – month: 09 year: 2018 text: 2018-September |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Eye & contact lens |
| PublicationTitleAlternate | Eye Contact Lens |
| PublicationYear | 2018 |
| Publisher | Contact Lens Association of Ophthalmologists, Inc |
| Publisher_xml | – name: Contact Lens Association of Ophthalmologists, Inc |
| References | Bron (R6-20230912) 2003; 22 Brignole-Baudouin (R16-20230912) 2011; 89 Lin (R14-20230912) 2012; 37 Chowdhury (R2-20230912) 2014; 348 Yildirim (R10-20230912) 2015; 19 Sullivan (R17-20230912) 2002; 506 (R4-20230912) 2007; 5 Luo (R5-20230912) 2005; 31 Galor (R18-20230912) 2014; 33 Feng (R8-20230912) 2015; 108 Pelajo (R7-20230912) 2010; 9 Yin (R13-20230912) 2011; 52 Bang (R15-20230912) 1999; 28 Stevenson (R3-20230912) 2012; 130 Baudouin (R9-20230912) 2013; 11 Autier (R1-20230912) 2014; 2 Kurtul (R12-20230912) 2015; 29 Reins (R19-20230912) 2015; 134 |
| References_xml | – volume: 29 start-page: 1081 year: 2015 ident: R12-20230912 article-title: The association of vitamin D deficiency with tear break-up time and Schirmer testing in non-Sjögren dry eye publication-title: Eye (Lond) doi: 10.1038/eye.2015.96 contributor: fullname: Kurtul – volume: 2 start-page: 76 year: 2014 ident: R1-20230912 article-title: Vitamin D status and ill health: A systematic review publication-title: Lancet Diabetes Endocrinol doi: 10.1016/S2213-8587(13)70165-7 contributor: fullname: Autier – volume: 52 start-page: 7359 year: 2011 ident: R13-20230912 article-title: Vitamin D enhances corneal epithelial barrier function publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.11-7605 contributor: fullname: Yin – volume: 31 start-page: 186 year: 2005 ident: R5-20230912 article-title: Hyperosmolar saline is a proinflammatory stress on the mouse ocular surface publication-title: Eye Contact Lens doi: 10.1097/01.ICL.0000162759.79740.46 contributor: fullname: Luo – volume: 5 start-page: 75 year: 2007 ident: R4-20230912 article-title: The definition and classification of dry eye disease: Report of the definition and classification subcommittee of the International Dry Eye WorkShop (2007) publication-title: Ocul Surf doi: 10.1016/S1542-0124(12)70081-2 – volume: 19 start-page: 49 year: 2015 ident: R10-20230912 article-title: Dry eye in vitamin D deficiency: More than an incidental association publication-title: Int J Rheum Dis doi: 10.1111/1756-185X.12727 contributor: fullname: Yildirim – volume: 9 start-page: 507 year: 2010 ident: R7-20230912 article-title: Vitamin D and autoimmune rheumatologic disorders publication-title: Autoimmun Rev doi: 10.1016/j.autrev.2010.02.011 contributor: fullname: Pelajo – volume: 33 start-page: 437 year: 2014 ident: R18-20230912 article-title: Effect of a Mediterranean dietary pattern and vitamin D levels on dry eye syndrome publication-title: Cornea doi: 10.1097/ICO.0000000000000089 contributor: fullname: Galor – volume: 28 start-page: 180 year: 1999 ident: R15-20230912 article-title: Reduced 25-hydroxyvitamin D levels in primary Sjögren's syndrome. Correlations to disease manifestations publication-title: Scand J Rheumatol doi: 10.1080/03009749950154266 contributor: fullname: Bang – volume: 89 start-page: e591 year: 2011 ident: R16-20230912 article-title: A multicentre, double-masked, randomized, controlled trial assessing the effect of oral supplementation of omega-3 and omega-6 fatty acids on a conjunctival inflammatory marker in dry eye patients publication-title: Acta Ophthalmol doi: 10.1111/j.1755-3768.2011.02196.x contributor: fullname: Brignole-Baudouin – volume: 130 start-page: 90 year: 2012 ident: R3-20230912 article-title: Dry eye disease: An immune mediated ocular surface disorder publication-title: Arch Ophthalmol doi: 10.1001/archophthalmol.2011.364 contributor: fullname: Stevenson – volume: 134 start-page: 101 year: 2015 ident: R19-20230912 article-title: Vitamin D: Implications for ocular disease and therapeutic potential publication-title: Exp Eye Res doi: 10.1016/j.exer.2015.02.019 contributor: fullname: Reins – volume: 348 start-page: g1903 year: 2014 ident: R2-20230912 article-title: Vitamin D and risk of cause specific death: Systematic review and meta-analysis of observational cohort and randomised intervention studies publication-title: BMJ doi: 10.1136/bmj.g1903 contributor: fullname: Chowdhury – volume: 11 start-page: 246 year: 2013 ident: R9-20230912 article-title: Role of hyperosmolarity in the pathogenesis and management of dry eye disease: Proceedings of the OCEAN group meeting publication-title: Ocul Surf doi: 10.1016/j.jtos.2013.07.003 contributor: fullname: Baudouin – volume: 22 start-page: 640 year: 2003 ident: R6-20230912 article-title: Grading of corneal and conjunctival staining in the context of other dry eye tests publication-title: Cornea doi: 10.1097/00003226-200310000-00008 contributor: fullname: Bron – volume: 506 start-page: 441 year: 2002 ident: R17-20230912 article-title: Correlations between nutrient intake and the polar lipid profiles of meibomian gland secretions in women with Sjogren's syndrome publication-title: Adv Exp Med Biol doi: 10.1007/978-1-4615-0717-8_62 contributor: fullname: Sullivan – volume: 108 start-page: 71 year: 2015 ident: R8-20230912 article-title: Lower serum 25 (OH) D concentrations in type 1 diabetes: A meta-analysis publication-title: Diabetes Res Clin Pract doi: 10.1016/j.diabres.2014.12.008 contributor: fullname: Feng – volume: 37 start-page: 871 year: 2012 ident: R14-20230912 article-title: Enhancement of vitamin D metabolites in the eye following vitamin D3 supplementation and UV-B irradiation publication-title: Curr Eye Res doi: 10.3109/02713683.2012.688235 contributor: fullname: Lin |
| SSID | ssj0020191 |
| Score | 2.3307967 |
| Snippet | OBJECTIVES:The aim of this study was to evaluate tear film function in patients with vitamin D deficiency.
METHODS:In a single center, 60 eyes of 30 patients... The aim of this study was to evaluate tear film function in patients with vitamin D deficiency. In a single center, 60 eyes of 30 patients with vitamin D... Objectives: The aim of this study was to evaluate tear film function in patients with vitamin D deficiency. Methods: In a single center, 60 eyes of 30 patients... OBJECTIVESThe aim of this study was to evaluate tear film function in patients with vitamin D deficiency.METHODSIn a single center, 60 eyes of 30 patients with... |
| SourceID | proquest crossref pubmed wolterskluwer |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | S62 |
| SubjectTerms | Adult Case-Control Studies Cross-Sectional Studies Dry Eye Syndromes - diagnosis Dry Eye Syndromes - etiology Dry Eye Syndromes - metabolism Female Humans Male Middle Aged Tears - metabolism Vitamin D Deficiency - complications Vitamin D Deficiency - metabolism |
| Title | Dry Eye Assessment in Patients With Vitamin D Deficiency |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/27660921 https://search.proquest.com/docview/1859721429 |
| Volume | 44 Suppl 1 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1La9tAEB4aB0pDKX3XbVK20JsQtZ67OhpbSQxuUohTchMraTcVbuQgSxT313dWq0echJIe6oOw1ngFM8M3s6NvZgA-C8m4lJ5vBr4UpiuEMDlTZCr07ixA_0BTlco-PqMnF2waumE_3qpf-6-axjXUtaqc_Qdtd5viAn5HneMVtY7XB-l9WmyMcCOMcddyU6U0vun2qYrtWv4wvmclv8LVKcKN6iChyi-3UvQbUZuE4rGrGkr0TP38eXGVFUnNAThaLcvqsoNsXnD1QiAs0koP80Kf2_E3Tn-vqzKp6vyrqtmSnTsIf2Y8yZa3f2kyERbrqFboSBr0VLU-Tj3gt4NX1zXqAaWGdQMnzxoIFs2ddy-a6y7Bs8lcd5lsP44uld5unn1yGh2ez-fRIrxY7MCujbjjDWB3PJnNZ90JHONZq62fDOiX-3bejk_uHDr24OmvleIxrJd1GcONYGTxHJ41pwgy1up_AY9E_hIef214Eq-AoRUQ1CLprYBkOWmtgCgrII0VkCnpreA1nB-Gi8mx2czIMBMHY3EztpgvfATtNFWd_6Xt-tLjicO80Ygz5lDpegFGIHbKEi-R1HHTQPhxQGM8h9vcc97AIF_l4h0Qbgcx417CHJbiH0QcSJ5ySiVG9RzjyCGYrWSia90KJWopDCjJ6LYkh_CpFV-EmKVeRPFcrKp1hDGiahqFodAQ3mq5djva1PdHgW0NwdoSdKTrgv_6xPcPeOIHeNLb7j4MyqISB7CzTquPjbX8Acb7cxs |
| link.rule.ids | 315,782,786,27935,27936 |
| linkProvider | Ovid |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Dry+Eye+Assessment+in+Patients+With+Vitamin+D+Deficiency&rft.jtitle=Eye+%26+contact+lens&rft.au=Demirci%2C+Goktug&rft.au=Karaman+Erdur%2C+Sevil&rft.au=Ozsutcu%2C+Mustafa&rft.au=Eliacik%2C+Mustafa&rft.date=2018-09-01&rft.eissn=1542-233X&rft.volume=44+Suppl+1&rft.spage=S62&rft.epage=S65&rft_id=info:doi/10.1097%2FICL.0000000000000325&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1542-2321&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1542-2321&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1542-2321&client=summon |