Synthesis and Antibacterial Activity of 3,4-Diaryl-5-(4-Guanidylsulfonylphenyl)-4,6-Dihydropyrrolo[3, 4-C]Pyrazol-6-Ones

Interaction of 1,4,5-trisubstituted tetrahydropyrrol-2,3-diones with hydrazine hydrate was used to synthesize 3,4-diaryl5-(4-guanidylsulfonylphenyl)-4,6-dihydropyrrolo[3,4- c ]pyrazol-6-ones. The antibacterial activity of these compounds was investigated.

Saved in:

Bibliographic Details
Published in:	Pharmaceutical chemistry journal Vol. 50; no. 1; pp. 16 - 18
Main Authors:	Bobrovskaya, O. V., Kovtonogova, I. V., Gein, V. L., Gein, L. F., Odegova, T. F.
Format:	Journal Article
Language:	English
Published:	New York Springer US 01-04-2016 Springer
Subjects:	Antibacterial agents Medicine Organic Chemistry Pharmacology/Toxicology Pharmacy Resveratrol synthesis antibacterial activity pyrazol-6-ones 3,4-diaryl5-(4-guanidylsulfonylphenyl)-4,6-dihydropyrrolo[3,4
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Interaction of 1,4,5-trisubstituted tetrahydropyrrol-2,3-diones with hydrazine hydrate was used to synthesize 3,4-diaryl5-(4-guanidylsulfonylphenyl)-4,6-dihydropyrrolo[3,4- c ]pyrazol-6-ones. The antibacterial activity of these compounds was investigated.
ISSN:	0091-150X 1573-9031
DOI:	10.1007/s11094-016-1390-5