Transcutaneous CO2 plateau as set-point for respiratory drive during upper airway flow-limitation

Highlights • Transcutaneous CO2 increases during progressive flow limitation. • Respiratory efforts during flow limitation remain low until tcCO2 plateau is reached. • Respiratory efforts during flow limitation increase when tcCO2 exceeds the plateau. • TcCO2 plateau may help to identify clinically...

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Bibliographic Details
Published in:Respiratory physiology & neurobiology Vol. 191; pp. 44 - 51
Main Authors: Rimpilä, Ville, Saaresranta, Tarja, Huhtala, Heini, Virkki, Arho, Salminen, Aaro V, Polo, Olli
Format: Journal Article
Language:English
Published: Elsevier B.V 15-01-2014
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Summary:Highlights • Transcutaneous CO2 increases during progressive flow limitation. • Respiratory efforts during flow limitation remain low until tcCO2 plateau is reached. • Respiratory efforts during flow limitation increase when tcCO2 exceeds the plateau. • TcCO2 plateau may help to identify clinically significant flow limitation.
ISSN:1569-9048
1878-1519
DOI:10.1016/j.resp.2013.10.014