pH-dependent behaviour of erythrocyte membrane elevations

Freeze-etch electron microscopy of human erythrocytes from heparinized normal blood reveals membrane elevations. These elevations disappear at low pH values and reappear under normal pH conditions in vitro, both in the absence and the presence of plasma. This pH-dependent behaviour is discussed as a...

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Bibliographic Details
Published in:	Cell biology international reports Vol. 2; no. 2; p. 139
Main Authors:	Goekoop, J G, Spies, F, Steeg, C B, Vrielink, R, Van Kempen, G M, De Vries, E
Format:	Journal Article
Language:	English
Published:	England 01-03-1978
Subjects:	Anticoagulants - pharmacology Citrates - pharmacology Edetic Acid - pharmacology Erythrocyte Membrane - drug effects Erythrocyte Membrane - ultrastructure Erythrocytes - ultrastructure Freeze Etching Heparin - pharmacology Humans Hydrogen-Ion Concentration Osmolar Concentration
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Summary:	Freeze-etch electron microscopy of human erythrocytes from heparinized normal blood reveals membrane elevations. These elevations disappear at low pH values and reappear under normal pH conditions in vitro, both in the absence and the presence of plasma. This pH-dependent behaviour is discussed as an intrinsic membrane event.
ISSN:	0309-1651
DOI:	10.1016/0309-1651(78)90034-6