Behavior of bioactive glass-ceramic implanted into long bone defects: a scintigraphic study

• Published in: Journal of pediatric orthopaedics. B Vol. 19; no. 1; pp. 102 - 107
• Main Authors: Šponer, Pavel, Urban, Karel, Urbanová, Elen, Karpaš, Karel, Mathew, Pradeep George
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins, Inc 01-01-2010
• Subjects: Adolescent; Bone and Bones - diagnostic imaging; Bone and Bones - surgery; Bone Cysts - diagnostic imaging; Bone Cysts - pathology; Bone Cysts - surgery; Bone Substitutes; Ceramics; Child; Curettage; Female; Humans; Male; Osseointegration; Prostheses and Implants; Radionuclide Imaging; Young Adult
• ISSN: 1060-152X; 1473-5865
• DOI: 10.1097/BPB.0b013e32832f06d5

The purpose of the study was to assess the long-term behavior and incorporation of the bioactive oxyhydroxyapatite glass-ceramic used to fill defects of long bones after curettage of bone cysts in 17 patients. The method of evaluation was a three-phase bone scintigraphy combined with radiographic and clinical evaluation. At a mean follow-up of 7 years, the glass-ceramic material had been completely incorporated. Mean uptake ratio was 1.31±0.25 after implantation of glass-ceramic in the metaphyseal region and 2.07±0.62 after implantation of glass-ceramic in the diaphyseal region (P<0.05). Mean uptake ratio was 1.40±0.30 in patients without persistent pain and 2.07±0.69 in patients who complained of pain in the area of synthetic filling (P<0.05). The bioactive glass-ceramic can be implanted into the metaphyseal defects of long bones, but this material is not suitable for filling the diaphyseal defects.