Base deficit in immediate postoperative period of coronary surgery with cardiopulmonary bypass and length of stay in intensive care unit

• Published in: Intensive care medicine Vol. 29; no. 2; pp. 257 - 261
• Main Authors: HUGOT, Pierre, SICSIC, Jean-Charles, SCHAFFUSER, Anne, SELLIN, Michel, CORBINEAU, Hervé, CHAPERON, Jacques, ECOFFEY, Claude
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer 01-02-2003; Berlin Springer Nature B.V
• Subjects: Acidosis - blood; Acidosis - epidemiology; Acidosis - etiology; Age Distribution; Aged; Analysis of Variance; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blood Gas Analysis - standards; Cardiopulmonary Bypass - adverse effects; Coronary Artery Bypass - adverse effects; Coronary Care Units - utilization; Emergency and intensive postoperative care (general aspects). Pathophysiology of surgery; France - epidemiology; Hospitals, University; Humans; Intensive care medicine; Length of Stay - statistics & numerical data; Logistic Models; Medical sciences; Middle Aged; Morbidity; Odds Ratio; Postoperative Period; Predictive Value of Tests; Prospective Studies; Risk Factors; Stroke Volume; Time Factors; France; Cardiopulmonary bypass; Human; Postoperative; Acid base balance; Surgery; Duration; Hospitalization; Intensive care unit
• ISSN: 0342-4642; 1432-1238
• DOI: 10.1007/s00134-002-1587-9

To assess the relationship between the base deficit value in the immediate postoperative period of coronary surgery for cardiopulmonary bypass and the length of stay in the ICU.
Prospective descriptive study in the department of anesthesia and cardiovascular surgery of a university hospital.
185 consecutive patients.
Coronary artery bypass graft with cardiopulmonary by pass.
Thirty variables were determined during the pre-, intra-, and postoperative periods; a statistical univariate analysis was performed differentiating patients whose length of stay in the ICU was 2 days or less and those whose stay was more than 2 days. Secondly, a logistic regression model was performed on the variables shown to have a statistically significant difference in univariate analysis, with determination of the odd ratio. Fourteen variables had a statistically significant difference in univariate analysis and three of them highlighted by the logistic regression model: administration of catecholamines, base deficit value in the 1st h postoperatively, and age with odd ratios, respectively, of 3.15, 1.51, and 1.07).
The value of base deficit measured during the 1st h after coronary surgery for cardiopulmonary bypass is correlated with the length of stay in ICU.