Drugs via enteral feeding tubes in inpatients: dispersion analysis and safe use of dispensers

• Published in: Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral Vol. 34; no. 2; pp. 257 - 263
• Main Authors: Beserra, Milena Pontes Portela, De Oliveira, Cristiani Lopes Capistrano Gonçalves, Portela, Mileyde Ponte, Lopes, Marcos Venícios de Oliveira, Fonteles, Marta Maria de França
• Format: Journal Article
• Language: English
• Published: Spain Grupo Arán 30-03-2017
• Subjects: Capsules; Dosage Forms; Enteral Nutrition - adverse effects; Enteral Nutrition - instrumentation; Humans; Inpatients; Nutrition & Dietetics; Patient Safety; Pharmaceutical Preparations - administration & dosage; Tablets; Tablets. Capsules. Enteral nutrition. Drug administration routes. Patient safety; Nutrición enteral; Seguridad del paciente; Capsules; Tablets; Enteral nutrition; Pastillas; Rutas de administración de fármacos; Patient safety; Cápsulas; Drug administration routes
• ISSN: 0212-1611; 1699-5198; 1699-5198
• DOI: 10.20960/nh.486

This study aimed to improve knowledge about drug administration through enteral feeding tubes (EFTs) in order to minimize efficacy and safety problems.
The study was performed in a public secondary care hospital with level II accreditation by the National Accreditation Organization (Organização Nacional de Acreditação ONA), in Fortaleza, Ceará, north-eastern Brazil.
One hundred and eight oral solid medications that could be administered through EFTs and were not available in liquid forms were evaluated via transformation of their solid dosage forms into liquid forms. Dispersion times and conditions were assessed to determine which medications should be crushed. We compared the use of dispensers and syringes and their connections to enteral feeding tubes and intravenous devices. Medications whose dispersion occurred within 20 minutes and could be visually perceived and whose content could be expelled without occluding the oral syringe were considered "satisfactory".
The dispersion was "satisfactory" in 82 (75.9%) of the medications; they were classified as capable of being dispersed in water in the oral syringe for further administration via EFTs without the need for crushing. Use the dispenser instead of the syringe for drug administration was safer because the dispenser apparatus did not fit into equipment for intravenous drug administration.