Treatment of Necrotizing Enterocolitis
To the Editor: The study by Moss et al. (May 25 issue) 1 is impressive because it represents a successful multicenter, prospective, randomized trial investigating therapies for necrotizing enterocolitis. However, 60 percent of the study cohort did not have evidence of pneumatosis on radiography, 77...
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| Published in: | The New England journal of medicine Vol. 355; no. 8; pp. 846 - 847 |
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| Format: | Journal Article |
| Language: | English |
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United States
Massachusetts Medical Society
24-08-2006
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| Abstract | To the Editor:
The study by Moss et al. (May 25 issue)
1
is impressive because it represents a successful multicenter, prospective, randomized trial investigating therapies for necrotizing enterocolitis. However, 60 percent of the study cohort did not have evidence of pneumatosis on radiography, 77 percent weighed less than 1000 g at birth, 30 percent were not receiving enteral feeding before perforation occurred, and more than 30 percent had perforation within the first two weeks after birth. These features suggest a diagnosis of spontaneous intestinal perforation rather than necrotizing enterocolitis.
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Several investigators have reported better outcomes with spontaneous intestinal perforation . . . |
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| AbstractList | To the Editor:
The study by Moss et al. (May 25 issue)
1
is impressive because it represents a successful multicenter, prospective, randomized trial investigating therapies for necrotizing enterocolitis. However, 60 percent of the study cohort did not have evidence of pneumatosis on radiography, 77 percent weighed less than 1000 g at birth, 30 percent were not receiving enteral feeding before perforation occurred, and more than 30 percent had perforation within the first two weeks after birth. These features suggest a diagnosis of spontaneous intestinal perforation rather than necrotizing enterocolitis.
2
–
4
Several investigators have reported better outcomes with spontaneous intestinal perforation . . . |
| Author | Gordon, Phillip V |
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| Cites_doi | 10.1016/S1072-7515(02)01344-3 10.1056/NEJMoa054605 10.1097/01.sla.0000164181.67862.7f 10.1038/sj.jp.7211439 10.1038/sj.jp.7211429 10.1038/sj.jp.7200269 |
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| Copyright | Copyright © 2006 Massachusetts Medical Society. All rights reserved. |
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| Snippet | To the Editor:
The study by Moss et al. (May 25 issue)
1
is impressive because it represents a successful multicenter, prospective, randomized trial... |
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| SubjectTerms | Diagnosis, Differential Enterocolitis, Necrotizing - diagnosis Enterocolitis, Necrotizing - therapy Humans Infant, Newborn Infant, Premature, Diseases - therapy Infant, Very Low Birth Weight Intestinal Perforation - diagnosis Intestinal Perforation - therapy Pneumatosis Cystoides Intestinalis |
| Title | Treatment of Necrotizing Enterocolitis |
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