X-chromosome genetic variation in São Paulo State (Brazil) population

• Published in: Annals of human biology Vol. 37; no. 4; pp. 598 - 603
• Main Authors: Martins, J. A., Silva, R. H. A., Freschi, A., Paneto, G. G., Oliveira, R. N., Cicarelli, R. M. B.
• Format: Journal Article
• Language: English
• Published: England Informa UK Ltd 01-08-2010
• Subjects: Brazil; Chromosomes, Human, X - genetics; Female; Gene Frequency - genetics; Genetic Variation; Genetics, Population; Humans; Male; Microsatellite Repeats - genetics; Brazil
• ISSN: 0301-4460; 1464-5033
• DOI: 10.3109/03014460903508512

Abstract
As data on X-chromosomal short tandem repeats (X-STRs) for the Brazilian population are scarse, the aim of this study was to determine the allele frequencies of five X-STRs (DXS6854, DXS7424, DXS101, DXS6808 and DXS7132) in the São Paulo State, Brazil. No deviations from the Hardy-Weinberg equilibrium were observed, with the exception of DXS101. The forensic efficiency parameters demonstrated that DXS101 was the most informative marker. Population comparisons revealed that the X-STR profile sampled in the state of São Paulo was more similar to European and African populations than Asiatic populations reported in this work.