Cancer immunotherapy and preclinical studies: why we are not wasting our time with animal experiments

Experimental research on the immune response to transplanted tumors has led to pioneering discoveries that laid many of the foundations for the current field of immunology. Experimental research in oncology has proven that murine and human tumors have antigens that are truly cancer specific. This ar...

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Bibliographic Details
Published in:	Hematology/oncology clinics of North America Vol. 20; no. 3; p. 567
Main Authors:	Schreiber, Karin, Rowley, Donald A, Riethmüller, Gert, Schreiber, Hans
Format:	Journal Article
Language:	English
Published:	United States 01-06-2006
Subjects:	Animal Experimentation Animals Drug Evaluation, Preclinical - methods Humans Immunotherapy - methods Neoplasms - therapy Therapeutic Human Experimentation
Online Access:	Get more information
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Summary:	Experimental research on the immune response to transplanted tumors has led to pioneering discoveries that laid many of the foundations for the current field of immunology. Experimental research in oncology has proven that murine and human tumors have antigens that are truly cancer specific. This article discusses research investigating how can antigens on cancer cells be used to help eradicate cancer.
ISSN:	0889-8588
DOI:	10.1016/j.hoc.2006.03.001