The level of Yop proteins secreted by Yersinia enterocolitica is changed in maltose mutants

• Published in: FEMS microbiology letters Vol. 204; no. 1; pp. 95 - 100
• Main Authors: Brzostek, Katarzyna, Raczkowska, Adrianna
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01-10-2001; Blackwell; Oxford University Press
• Subjects: Bacterial Outer Membrane Proteins - metabolism; Bacterial Outer Membrane Proteins - secretion; Bacteriology; Biological and medical sciences; Culture Media; DNA Transposable Elements; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Bacterial; Human protozoal diseases; Infectious diseases; Malaria; Maltose; Maltose - genetics; Maltose - metabolism; Maltose system; Medical sciences; Microbiology; Mutation; Parasitic diseases; Pathogenicity; Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains; Pathogens; Protein Tyrosine Phosphatases - metabolism; Protein Tyrosine Phosphatases - secretion; Proteins; Protozoal diseases; Secretion; Transcription; Transcription, Genetic; Yersinia enterocolitica; Yersinia enterocolitica - genetics; Yersinia enterocolitica - physiology; Yop protein; yop proteins; yopH gene; Maltose system; Yop protein; Production system; Sound production; Secretion; Transposon; Insertion; Maltose; Protein A; Plasmid; Pathogenicity; Yersinia enterocolitica; Pathogenic; Bacteria; Mutation; Transport; Enterobacteriaceae
• ISSN: 0378-1097; 1574-6968
• DOI: 10.1111/j.1574-6968.2001.tb10869.x

Abstract
Enteropathogenic Yersinia enterocolitica strains express a set of plasmid-encoded proteins called Yops, involved in pathogenicity. We studied the influence of the maltose system on the production of Yop proteins and found that the level of Yop proteins of Y. enterocolitica O:9 was reduced in the presence of maltose. Transposon insertion mutants impaired with the maltose transport activity showed a decreased level in the production of Yop proteins. The transcription of the yopH gene for YopH phosphatase in these maltose mutants was unchanged and revealed a maltose mutation impaired in the secretion of Yop proteins instead of their expression.