Aptamers: Features, Synthesis and Applications

• Published in: Chemistry & biodiversity Vol. 20; no. 10; pp. e202301008 - n/a
• Main Authors: P. U, Aiswarya, Raj, Gopika, John, Jinju, Mohan K, Malavika, John, Franklin, George, Jinu
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 01-10-2023
• Subjects: Antibodies; Aptamers; Biomedical materials; Biosensors; diagnosis; Drug delivery; SELEX; sensors; targeted drug delivery; therapeutics
• ISSN: 1612-1872; 1612-1880; 1612-1880
• DOI: 10.1002/cbdv.202301008

Aptamers have become a topic of interest among the researchers and scientists since they not only possess all of the benefits of antibodies but also possess special qualities including heat stability, low cost, and limitless uses⋅ Here we give a review about the features, applications, and challenges of aptamers and also how they are beneficial over the antibodies for biomedical applications. Their unique features make aptamers a prominent tool in therapeutics, diagnostics, biosensors and targeted drug delivery. In conclusion, aptamers represent exciting materials for a variety of applications and can be modified to improve their properties and to extend their applications in biomedical field.