Cardiovascular collapse associated with nitrous oxide anaesthetic: a case report

This is a case report of a one year old infant weighing 6.7 kilograms with a preoperative diagnosis of partial anomalous pulmonary venous drainage whose anaesthetic was complicated by cardiovascular collapse following addition of nitrous oxide to oxygen administered to the patient using a T-piece br...

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Bibliographic Details
Published in:	Canadian Anaesthetists' Society journal Vol. 29; no. 5; pp. 484 - 488
Main Authors:	Davidson, J R, Chinyanga, H M
Format:	Journal Article
Language:	English
Published:	Canada 01-09-1982
Subjects:	Anesthesia - adverse effects Atropine - adverse effects Glycopyrrolate - adverse effects Heart Defects, Congenital - surgery Humans Infant Methylprednisolone Hemisuccinate - adverse effects Morphine - adverse effects Nitrous Oxide - adverse effects Shock - chemically induced
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Summary:	This is a case report of a one year old infant weighing 6.7 kilograms with a preoperative diagnosis of partial anomalous pulmonary venous drainage whose anaesthetic was complicated by cardiovascular collapse following addition of nitrous oxide to oxygen administered to the patient using a T-piece breathing circuit. The cardiovascular pathopharmacology of all the drugs administered to the patient before the event as well as that of nitrous oxide is discussed in detail. The drugs discussed are atropine 0.1 mg (0.01 mg . kg-1), glycopyrrolate 0.07 mg (0.01 mg . kg-1), morphine 0.9 mg (0.14 mg . kg-1) methylprednisone sodium succinate 165 mg (23.5 mg . kg-1) sodium thiopentone 40 mg (5.7 mg . kg-1), metocurine 3.4 mg (0.4 mg . kg-1).
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0008-2856 1496-8975
DOI:	10.1007/BF03009414