Characteristic Ratio-Independent Arterial Stiffness-Based Blood Pressure Estimation

• Published in: IEEE journal of biomedical and health informatics Vol. 21; no. 5; pp. 1263 - 1270
• Main Authors: Baktash, Seddigheh, Forouzanfar, Mohamad, Batkin, Izmail, Bolic, Miodrag, Groza, Voicu Z., Ahmad, Saif, Dajani, Hilmi R.
• Format: Journal Article
• Language: English
• Published: United States IEEE 01-09-2017; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Adult; Algorithms; Arterial stiffness (AS); Arteries; Biomedical monitoring; Blood pressure; blood pressure (BP); Blood Pressure - physiology; Blood Pressure Determination - methods; Cardiovascular diseases; Curve fitting; Disease control; Estimation; Female; Heart; Humans; Hypertension; Male; Mathematical model; mathematical modeling; Mathematical models; Measurement techniques; Measuring instruments; Middle Aged; Models, Cardiovascular; non-invasive blood pressure measurement; oscillometry; Oscillometry - methods; Parameter estimation; Pulse Wave Analysis - methods; Signal Processing, Computer-Assisted; Stiffness; Transit time; Vascular Stiffness - physiology; Young Adult
• ISSN: 2168-2194; 2168-2208
• DOI: 10.1109/JBHI.2016.2594177

Noninvasive blood pressure (BP) measurement is an important tool for managing hypertension and cardiovascular disease. However, automated noninvasive BP measurement devices, which are usually based on the oscillometric method, do not always provide accurate estimation of BP. It has been found that change in arterial stiffness (AS) is an underlying mechanism of disagreement between an oscillometric BP monitor and a sphygmomanometer. This problem is addressed by incorporating parameters related to AS in the algorithm for BP measurement. Pulse transit time (PTT) is first used to estimate AS parameters, which are fixed into a model of the oscillometric envelope. This model can then be used to perform curve fitting to the measured signal using only four parameters: systolic BP, diastolic BP, mean BP, and lumen area at zero transmural pressure. The proposed technique is independent of the experimentally determined characteristic ratios that are commonly used in existing oscillometric methods. The accuracy of the proposed technique was evaluated by comparing with the same model without incorporation of AS, and with reference BP device measurements. The new method achieved standard deviation of error less than 8 mmHg and mean error less than 5 mmHg. The results show consistency with ANSI/AAMI SP-10 standard for noninvasive BP measurement techniques.