Pathophysiology of Peyronie's disease

Peyronie's disease is an inflammatory condition characterized by the formation of fibrous, noncompliant nodules in the tunica albuginea which can impede tunical expansion during penile erection, leading to deformity and bending. While the cause of this disease is thought to be due to microvascu...

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Bibliographic Details
Published in:International journal of impotence research Vol. 14; no. 5; pp. 406 - 410
Main Authors: Moreland, R B, Nehra, A
Format: Journal Article
Language:English
Published: England Nature Publishing Group 01-10-2002
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Summary:Peyronie's disease is an inflammatory condition characterized by the formation of fibrous, noncompliant nodules in the tunica albuginea which can impede tunical expansion during penile erection, leading to deformity and bending. While the cause of this disease is thought to be due to microvascular trauma and abnormal wound healing, other hypotheses include genetic predisposition. In this review the pathophysiology of Peyronie's disease is discussed as well as current hypotheses regarding its origin.
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ISSN:0955-9930
1476-5489
DOI:10.1038/sj.ijir.3900875