Age changes of calcaneal ultrasonometry in healthy German women

• Published in: Calcified tissue international Vol. 65; no. 2; pp. 117 - 120
• Main Authors: Hadji, P, Hars, O, Bock, K, Albert, U, Beckmann, M W, Emons, G, Schulz, K
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 01-08-1999
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Aging - physiology; Body Constitution; Bone Density; Calcaneus - diagnostic imaging; Cross-Sectional Studies; Female; Germany; Humans; Menopause - metabolism; Middle Aged; Osteoporosis, Postmenopausal - epidemiology; Premenopause - metabolism; Reproducibility of Results; Ultrasonography
• ISSN: 0171-967X; 1432-0827
• DOI: 10.1007/s002239900667

This study assessed age changes in quantitative ultrasound sonometry (QUS) in a large sample of healthy German women. Speed of sound (SOS), broadband ultrasound attenuation (BUA), and stiffness index (SI) of the calcaneus were measured in 1333 women (mean age 50.5 +/- 11.5 years) using the Achilles ultrasonometer (Lunar Corp., Madison, WI, USA). The short-term precision in 31 adults was 0.2% for SOS, 1. 2% for BUA, and 1.3% for SI. There was an overall decline of 15% for BUA, 4% for SOS, and 31% for SI between late adolescence and old age. In premenopausal women, BUA decreased only slightly (-3%), whereas postmenopausal women showed a significantly increased decline (-12%). In contrast, SOS continuously decreased from the age of 15; there was a decline of 2% from adolescence to the menopause; postmenopausal women showed a slightly larger decline (-2.5%). The SI of premenopausal women decreased by 10%, but the postmenopausal decline of almost 22% was significantly greater. SI values for premenopausal German women were comparable to those observed in the American Achilles reference population, but postmenopausal German women had significantly higher SI values of 7% due to a lower rate of aging loss.