Electrospun biomedical nanofibers and their future as intelligent biomaterials

• Published in: Current opinion in biomedical engineering Vol. 24; p. 100418
• Main Authors: Lugoloobi, Ishaq, Yuanhao, Wang, Marriam, Ifra, Hu, Jinming, Tebyetekerwa, Mike, Ramakrishna, Seeram
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01-12-2022
• Subjects: Biomedical applications; Electrospinning; Intelligent materials; Nanofibers; Electrospinning; Biomedical applications; Intelligent materials; Nanofibers
• ISSN: 2468-4511; 2468-4511
• DOI: 10.1016/j.cobme.2022.100418

Electrospinning is one of the most studied techniques for the facile, versatile, and scalable synthesis of nano/micro/macro-fibers. The process employs various polymers of natural and synthetic origin for the preparation of fibers with several immeasurable designs, in virgin and composite forms. Bestowed with alluring properties such as solubility/solvolysis, biocompatibility, and degradability, electrospun fibers have found numerous applications as biomedical materials for tissue engineering, localized therapy, wound dressing, and drug delivery. Their properties enable effortless and precise compounding with various biopharmaceuticals and nanomaterials that are sensitive to chemo-, magnetic-, and photo-cathartic modalities. We hence provide a summarized insight into the recent past and predict the future of electrospun nanofibers as intelligent systems for biomedical applications.