Evaluating the benefit of virtual surgical planning on bony union rates in head and neck reconstructive surgery

• Published in: Head & neck Vol. 46; no. 6; pp. 1322 - 1330
• Main Authors: Sabiq, Farahna, Cherukupalli, Abhiram, Khalil, Mohammad, Tran, Linh K., Kwon, Jamie J. Y., Milner, Thomas, Durham, James S., Prisman, Eitan
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01-06-2024; Wiley Subscription Services, Inc
• Subjects: Apposition; Head & neck cancer; Head and neck; head and neck cancer; Reconstructive surgery; three‐dimensional imaging; three‐dimensional printing; virtual surgical planning; virtual surgical planning; three‐dimensional imaging; head and neck cancer; three‐dimensional printing; reconstructive surgery
• ISSN: 1043-3074; 1097-0347; 1097-0347
• DOI: 10.1002/hed.27759

Objectives
Virtual surgical planning (VSP) has gained acceptance because of its benefits in obtaining adequate resection, achieving cephalometric accuracy, and reducing operative time. The aim of this study is to compare the rate of union between VSP and free‐hand surgery (FHS), identify predictors of non‐union and evaluate the difference in operative time.
Methods
Post‐operative CT were retrospectively reviewed for 123 patients who underwent maxillary or mandibular reconstruction between 2014 and 2021 using either VSP or FHS. Each apposition was graded as complete, partial or non‐union. The rate of union, risk difference and inter‐rater reliability were calculated. The difference in operative time was assessed. Predictors of non‐union were identified using logistic regression.
Results
A total of 326 appositions were graded (VSP n = 150; FHS n = 176). The rates of complete and partial union were higher with VSP than FHS (74.7% vs. 65.3%; 18% vs. 15.9%, respectively, p = 0.01). Non‐union was found at a higher rate with FHS than with VSP (18.7% vs. 7.3%). The non‐union risk difference was 11.4. FHS, major complications and apposition at the native bone were predictors of non‐union (OR 2.9, p = 0.02; OR 3.4, p = 0.01; OR 2.5, p = 0.05, respectively). The mean surgical time was shorter with VSP than with FHS (265.3 vs. 381.5 min, p < 0.001). The inter‐rater agreement was high (k = 0.85; ICC = 0.86).
Conclusion
VSP demonstrated significantly higher bony union rates and shorter operative time. FHS, development of major complications and apposition with native bone correlated with non‐union.