Morphogenesis: Multitalented GTPases Seeking New Jobs

Since their discovery twenty years ago the GTPases Rac, Rho, and Cdc42 have become cellular superstars, with diverse roles in regulating actin, cell polarity and other functions. Several recent papers highlight their roles in morphogenesis, revealing surprising complexity.

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Bibliographic Details
Published in:	Current biology Vol. 19; no. 21; pp. R985 - R987
Main Authors:	Sawyer, Jessica K., Harris, Nathan J., Peifer, Mark
Format:	Journal Article
Language:	English
Published:	England Elsevier Inc 17-11-2009
Subjects:	Animals Compound Eye, Arthropod - enzymology Drosophila melanogaster - enzymology Drosophila melanogaster - growth & development Drosophila Proteins - physiology GTP-Binding Proteins - physiology Morphogenesis Pupa - enzymology Pupa - growth & development rho GTP-Binding Proteins - physiology Wings, Animal - enzymology
Online Access:	Get full text
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Description
Summary:	Since their discovery twenty years ago the GTPases Rac, Rho, and Cdc42 have become cellular superstars, with diverse roles in regulating actin, cell polarity and other functions. Several recent papers highlight their roles in morphogenesis, revealing surprising complexity.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0960-9822 1879-0445
DOI:	10.1016/j.cub.2009.09.060