Hemodynamic changes in limb shaking TIA associated with anterior cerebral artery stenosis

• Published in: Neurology Vol. 63; no. 8; pp. 1519 - 1521
• Main Authors: HAN, S. W, KIM, S. H, KIM, J. K, PARK, C. H, YUN, M. J, HEO, J. H
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 26-10-2004
• Subjects: Acetazolamide; Anterior Cerebral Artery - diagnostic imaging; Anterior Cerebral Artery - pathology; Anterior Cerebral Artery - physiopathology; Anticoagulants - therapeutic use; Biological and medical sciences; Carbonic Anhydrase Inhibitors; Cerebral Angiography; Cerebrovascular Circulation - drug effects; Cerebrovascular Circulation - physiology; Constriction, Pathologic - complications; Constriction, Pathologic - pathology; Constriction, Pathologic - physiopathology; Corpus Callosum - blood supply; Corpus Callosum - diagnostic imaging; Corpus Callosum - pathology; Female; Gyrus Cinguli - blood supply; Gyrus Cinguli - diagnostic imaging; Gyrus Cinguli - pathology; Humans; Infarction, Anterior Cerebral Artery - diagnostic imaging; Infarction, Anterior Cerebral Artery - pathology; Infarction, Anterior Cerebral Artery - physiopathology; Ischemic Attack, Transient - complications; Ischemic Attack, Transient - pathology; Ischemic Attack, Transient - physiopathology; Leg - physiopathology; Magnetic Resonance Imaging; Medical sciences; Middle Aged; Movement Disorders - etiology; Movement Disorders - pathology; Movement Disorders - physiopathology; Neurology; Orthopedic surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Vascular diseases and vascular malformations of the nervous system; Stenosis; Nervous system diseases; Hemodynamics; Anterior cerebral artery; Shaking
• ISSN: 0028-3878; 1526-632X
• DOI: 10.1212/01.WNL.0000142087.24542.58

Limb shaking TIA is a rare but well-known feature of severe carotid artery stenosis. The authors report a patient who developed recurrent shaking movements of a leg. An angiogram showed the focal stenosis of the anterior cerebral artery. Ictal and postacetazolamide SPECT scans suggested a local hyperfunction of cortical neurons and an impaired hemodynamic reserve in the vicinity of the ischemic area.