Hydantoin derivatives. A new class of inhibitors of human leukocyte elastase

Derivatives of hydantoin have been found to inactivate human leukocyte elastase irreversibly. Chymotrypsin and cathepsin G are also inhibited by these compounds.

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Bibliographic Details
Published in:	Journal of enzyme inhibition Vol. 3; no. 3; p. 237
Main Authors:	Groutas, W C, Stanga, M A, Castrisos, J C, Schatz, E J
Format:	Journal Article
Language:	English
Published:	Switzerland 1990
Subjects:	Amino Acid Sequence Humans Hydantoins - chemical synthesis Hydantoins - pharmacology Indicators and Reagents Kinetics Leukocytes - enzymology Molecular Sequence Data Oligopeptides - pharmacology Pancreatic Elastase - antagonists & inhibitors Pancreatic Elastase - blood Protease Inhibitors - chemical synthesis
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Description
Summary:	Derivatives of hydantoin have been found to inactivate human leukocyte elastase irreversibly. Chymotrypsin and cathepsin G are also inhibited by these compounds.
ISSN:	8755-5093
DOI:	10.3109/14756369009035842