Enhancement of 6-gingerol extraction from Bentong ginger using supercritical carbon dioxide

• Published in: Journal of CO2 utilization Vol. 72; p. 102505
• Main Authors: Kamaruddin, Muhamad Syafiq Hakimi, Chong, Gun Hean, Umanan, Fizreena, Suleiman, Norhidayah
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01-06-2023
• Subjects: 6-gingerol; Antioxidant activity; Bentong ginger; Phenolic compound; Scco2; 6-gingerol; Phenolic compound; Bentong ginger; Scco2; Antioxidant activity
• ISSN: 2212-9820; 2212-9839
• DOI: 10.1016/j.jcou.2023.102505

Supercritical carbon dioxide extraction is a green technology. It was used to isolate 6-gingerol from Bentong ginger (Zingiber officinale Roscoe var. Bentong). A central composite design (CCD) was employed to investigate and optimize three process conditions, namely the extraction pressure (10–30 MPa), temperature (40–60 °C), and particle size of the sample (300–600 µm). The method was used to model the extraction of 6-gingerol, total phenolic content, total flavonoid content, and antioxidant activity determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH). The optimum conditions were estimated to be a pressure of 25 MPa, a temperature of 40 °C, and a particle size of 300 µm. The highest values for 6-gingerol content (171.26 mg/g), total phenolic content (17.84 GAE mg/g), total flavonoid content (74.46 QE mg/g), and radical-scavenging activity (91.14%) of dried Bentong ginger were achieved at these optimized conditions. The good fit between predicted and experimental values shows the fitness of the model employed for estimating the optimum conditions for Bentong ginger extraction. Moreover, the scCO2 system at the conditions studied was more effective than the conventional Soxhlet method for the extraction of bioactive compounds.
•scCO2 extraction is capable to extract 6-gingerol from Bentong ginger at optimum condition by altering the CO2 density.•Bentong ginger is a good source of 6-gingerol in comparable with other type of ginger variant.•6-gingerol from Bentong ginger can be transformed to shogaol compound at higher temperature.