Clinical recommendations for non-invasive ultrasound neuromodulation

• Published in: Brain stimulation Vol. 17; no. 4; pp. 890 - 895
• Main Authors: Beisteiner, Roland, Lozano, Andres, Di Lazzaro, Vincenzo, George, Mark S., Hallett, Mark
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-07-2024; Elsevier
• Subjects: Brain - diagnostic imaging; Brain - physiology; Focused ultrasound; Humans; Recommendations; Transcranial pulse stimulation; Transcranial ultrasonic stimulation; Ultrasonic Therapy - methods; Ultrasound therapy; Recommendations; Focused ultrasound; Ultrasound therapy; Transcranial ultrasonic stimulation; Transcranial pulse stimulation
• ISSN: 1935-861X; 1876-4754; 1876-4754
• DOI: 10.1016/j.brs.2024.07.013

Non-invasive ultrasound neuromodulation has experienced exponential growth in the neuroscientific literature, recently also including clinical studies and applications. However, clinical recommendations for the secure and effective application of ultrasound neuromodulation in pathological brains are currently lacking. Here, clinical experts with neuroscientific expertise in clinical brain stimulation and ultrasound neuromodulation present initial clinical recommendations for ultrasound neuromodulation with relevance for all ultrasound neuromodulation techniques. The recommendations start with methodological safety issues focusing on technical issues to avoid harm to the brain. This is followed by clinical safety issues focusing on important factors concerning pathological situations.
•First Clinical Expert Recommendations for Ultrasound Neuromodulation as a new Brain Therapy.