Platelet-rich Fibrin Potential Role in Periodontal Regeneration A Review Study

• Published in: Medical Journal of Babylon Vol. 20; no. 1; pp. 1 - 6
• Main Authors: Al-Rihaymee, Sarah, Mahmood, Maha
• Format: Journal Article
• Language: English
• Published: Medknow Publications and Media Pvt. Ltd 01-01-2023; Wolters Kluwer Medknow Publications
• Subjects: Analysis; Care and treatment; Fibrin; growth factors; Health aspects; Methods; periodontal regeneration; Periodontitis; platelet concentrates; prf; Regeneration (Biology); Iraq
• ISSN: 1812-156X; 2312-6760
• DOI: 10.4103/MJBL.MJBL_237_22

Periodontitis is a persistent bacterial-causing disease which damages the supporting periodontium of the teeth. The complexity of supporting tissue structure makes the regeneration a challenge for periodontists. Early investigations were focused on discovering therapeutic substitutes that are biocompatible, simple to prepare and economic. This might cause a local release of growth factors that accelerate the healing process of the soft and hard tissue. Recently, platelet-rich fibrin (PRF) has received a wide attention as a biocompatible regenerative material in both dental and medical fields. PRF is a natural fibrin-derived biomaterial, and it is easy to obtain. It can be gotten from individual blood without the use of any external anticoagulant. The principle of PRF technology use in the regeneration process is to use patients’ blood to extract all the growth factors which promote regeneration of tissue by accelerating the healing process. The main objective of this review is to concisely illustrate PRF and its contribution in periodontal regeneration.