Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report

• Published in: Vojnosanitetski pregled Vol. 74; no. 3; pp. 278 - 281
• Main Authors: Vukovic-Ercegovic, Gordana, Perkovic-Vukcevic, Natasa, Djordjevic, Snezana, Segrt, Zoran, Potrebic, Olivera, Jankovic, Snezana, Jovic-Stosic, Jasmina, Marinkovic, Nadica
• Format: Journal Article
• Language: English
• Published: Military Health Department, Ministry of Defance, Serbia 01-01-2017
• Subjects: calcium channel blockers; fat emulsions, intravenous; heart block; poisoning; suicide; treatment outcome; verapamil
• ISSN: 0042-8450; 2406-0720
• DOI: 10.2298/VSP150901010V

Introduction. During the last few years, intravenous lipid emulsions have
been effectively used in treatment of acute poisonings with lipophilic
substances, including verapamil. Case report. A 37-year-old women presented 1
hour after ingestion of 2.8 g verapamil with hypotension and complete heart
block. Because of the applied standard therapy failure and further patients
impairment, Intralipid? 20% was used. Sinus rhythm was restored, arterial
blood pressure increased and verapamile concentrations, both total and free
decreased. Conclusion. Intravenous lipid emulsion can be important in
treatment of severe acute intoxication and cardiotoxicity caused by
verapamil.
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