Meteorological parameters and hospitalizations of patients with sickle cell anemia: a 20-year retrospective study in Campinas, São Paulo, Brazil

• Published in: International journal of environmental health research Vol. 33; no. 12; pp. 1430 - 1442
• Main Authors: Alagbe, Adekunle Emmanuel, Corozolla, Welington, Samejima Teixeira, Liriam, Peres Coelho, Raissa, Heuminski de Avila, Ana Maria, Paro Costa, Paula Dornhofer, Fatima Sonati, Maria, de Faria, Eliana Cotta, Nunes Dos Santos, Magnun Nueldo
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01-12-2023; Taylor & Francis LLC
• Subjects: Adult; Adults; Anemia; Anemia, Sickle Cell - epidemiology; Brazil - epidemiology; Child; Children; Climate; Crises; environmental parameters; Hospitalization; Humans; ICD-10; Meteorological parameters; Retrospective Studies; Sickle cell anemia; Sickle cell disease; Young Adult; Brazil; ICD-10; Sickle cell anemia; hospitalization; meteorological parameters; environmental parameters
• ISSN: 0960-3123; 1369-1619
• DOI: 10.1080/09603123.2022.2098258

To investigate the influence of climate on hospitalizations of sickle cell anemia (SCA) adults and children, we analyzed the health and meteorological parameters from a metropolis (1999-2018). 1462 hospitalizations were coded for SCA patients in crisis (M:F = 715:747) and 1354 hospitalizations for SCA patients without crisis (M:F = 698:656) [age = 22.9 vs 15.2 years and duration of hospitalization (DoH) = 5.7 vs 4.4 days, respectively,]. More hospitalizations were for adults than children in crisis, and for children than adults without crisis. More children and adults were hospitalized in winter andspring than in summer and autumn     Hospitalizations correlated positively with humidity (lag −5), maximum pressure (lag −2), mean pressure (lag −2), and thermal amplitude (lag −2), and negatively with maximum temperature (lag −3). DoH positively correlated with minimum temperature (lag −4). Understanding these complex associations would induce attitudinal/behavioral modifications among patients and their caregivers.