Unicentric Castleman's disease as a localized retroperitoneal mass: A case report and review of literature

• Published in: International journal of applied and basic medical research Vol. 8; no. 4; pp. 259 - 262
• Main Authors: Gopi, Praveen, Potty, Vasudevan, Kaurav, Rustam, Govindan, Krishna
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01-10-2018; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd
• Subjects: Abdomen; Analysis; Autoimmune diseases; Care and treatment; Case Report; Case reports; Case studies; Consent; Disease; Health aspects; Histology, Pathological; Immune system; Immunologic diseases; Lymphatic system; Medical imaging; Medical prognosis; Pain; Patients; Pulmonary arteries; Radiation therapy; Treatment outcome; Urine; Women; Castleman's disease; hyaline type; retroperitoneum; unicentric
• ISSN: 2229-516X; 2248-9606
• DOI: 10.4103/ijabmr.IJABMR_256_17

Castleman's disease (CD) is a rare disorder characterized by proliferation of the lymphoid tissue. Clinically, it presents in two forms either a unicentric (UC) or multicentric. Mediastinum is the most common location. UC retroperitoneal presentation is rare. We report a case of 29-year-old female who presented with left loin pain, and on abdominal imaging, evaluation identified a retroperitoneal mass in the left hypochondrium in the pararenal space. Mass was surgically excised entirely. Histopathological examination demonstrated hyaline vascular type of CD. CD should be considered in differential diagnosis of retroperitoneal mass, especially in equivocal cases. We also reviewed literature of 134 cases of retroperitoneal CD to analyze the presentation, management, and outcome.