Can morphological changes of erythrocytes be driven by hemoglobin?

At 49 °C erythrocytes undergo morphological changes due to an internal force, but the origin of the force that drives changes is not clear. Here we propose that our recent experiments on thermally induced force-release in hemoglobin (Gevorkian, 2015) can provide an explanation for the morphological...

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Bibliographic Details
Published in:Physica A Vol. 508; pp. 608 - 612
Main Authors: Gevorkian, S.G., Allahverdyan, A.E., Gevorgyan, D.S., Ma, Wen-Jong, Hu, Chin-Kun
Format: Journal Article
Language:English
Published: Elsevier B.V 15-10-2018
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Summary:At 49 °C erythrocytes undergo morphological changes due to an internal force, but the origin of the force that drives changes is not clear. Here we propose that our recent experiments on thermally induced force-release in hemoglobin (Gevorkian, 2015) can provide an explanation for the morphological changes of erythrocytes. •The force driving the morphological changes of erythrocytes (MCE) at 49°C is not clear.•The hemoglobin has thermally induced force-release at 49°C (Gevorkian et. al., 2015).•The thermally induced force-release in hemoglobin at 49°C provides the force for the MCE at 49°C.
ISSN:0378-4371
1873-2119
DOI:10.1016/j.physa.2018.05.118