Synthesis of new nano Schiff base complexes: X-ray crystallography, thermal, electrochemical and anticancer studies of nano uranyl Schiff base complexes

• Published in: Bulletin of the Chemical Society of Ethiopia Vol. 32; no. 1; pp. 89 - 100
• Main Authors: D. Firuzabadi, F., Asadi, Z., Yousefi, R.
• Format: Journal Article
• Language: English
• Published: Chemical Society of Ethiopia 01-01-2018
• Subjects: Anticancer activities; Chemical properties; Chemical synthesis; Electrochemistry; X-ray crystallography; Methods; Production processes; Schiff bases; Thermal studies; Uranyl Schiff base complex
• ISSN: 1011-3924; 1726-801X
• DOI: 10.4314/bcse.v32i1.8

This study presents synthesis and characterization of new nano uranyl Schiff base complexes. Electrochemistry of these complexes showed a quasireversible redox reaction without any successive reactions. Furthermore, X-ray crystallography exhibited that beside the coordination of tetradentate Schiff base, one solvent molecule (dimethylformamide) was also coordinated. According to Coats-Redfern plots the kinetics of thermal decomposition of the studied complexes was first-order in all stages. Anticancer activities of the uranyl Schiff base complexes against cancer cell lines (Jurkat) was studied and determined by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazoliumbromide) assay. The results demonstrated that the complexes with aliphatic bridging units showed less anticancer activities than those having the aromatic units. KEY WORDS: Uranyl Schiff base complex, Anticancer activities, Thermal studies, Electrochemistry; X-ray crystallography