Dengue epidemic in the state of Rio de Janeiro, Brazil: virological and epidemiological aspects

• Published in: Revista do Instituto de Medicina Tropical de São Paulo Vol. 35; no. 2; pp. 149 - 154
• Main Authors: MIAGOSTOVICH, M. P, NOGUEIRA, R. M. R, CAVALCANTI, S. M. B, MARZOCHI, K. B. F, SCHATZMAYR, H. G
• Format: Journal Article
• Language: English
• Published: São Paulo Instituto de Medicina Tropical de São Paulo 01-04-1993; Instituto de Medicina Tropical
• Subjects: Adolescent; Adult; Age Distribution; Arboviroses; Biological and medical sciences; Brazil - epidemiology; Child; Child, Preschool; Dengue - epidemiology; Dengue - microbiology; Dengue fevers; Dengue Virus - isolation & purification; Female; Human viral diseases; Humans; Infant; Infant, Newborn; Infectious diseases; Male; Medical sciences; Middle Aged; Seasons; Sex Distribution; Time Factors; TROPICAL MEDICINE; Tropical viral diseases; Viral diseases; South America; Brazil; America; Infection; Human; Antibody; Immunological investigation; Viral disease; Dengue; Virological exploration; Arbovirus disease; Serology; Epidemiology; DEN-1 Virus isolation; Brazil
• ISSN: 0036-4665; 1678-9946; 1678-9946; 0036-4665
• DOI: 10.1590/s0036-46651993000200006

Laboratory studies were carried out on 3178 patients with signs and symptoms suggestive of dengue infection from April 1986 to December 1987 in the State of Rio de Janeiro, Brazil. The epidemic had two peaks following the first virus isolation and affected the inhabitants of 17 counties. Both sex and all age groups were affected. Dengue virus type 1 was isolated from 1039 sera and the number of confirmed cases was increased to 1874 (59%) by MAC-ELISA. Isolation rate confirmed cases reached 80% in the specimens obtained until the 4th day after the onset of disease and viraemia ranged from 10(3.0) to 10(8.5) TCID50/ml.