Buffer and sugar concentration dependent fluorescence response of a BODIPY-based aryl monoboronic acid sensor

The emission intensity response from a BODIPY-based aryl monoboronic acid was found to depend on the employed buffer at physiological pH (7.4). The structural prerequisites of the bound monosaccharides showed a clear discrimination between d-glucose and d-fructose. The different response behavior wa...

Full description

Saved in:

Bibliographic Details
Published in:	Tetrahedron letters Vol. 53; no. 44; pp. 5852 - 5855
Main Authors:	Hansen, J.S., Petersen, J.F., Hoeg-Jensen, T., Christensen, J.B.
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 31-10-2012
Subjects:	Aromatic compounds Arylboronic acid Buffered conditions Buffers Colorimetric reporter Correlation analysis Discrimination Emission Fluorescence Fluorescent reporter Monosaccharides Structural feature Tetrahedrons Buffered conditions BVXCAFRMJGXODV-UHFFFAOYSA-N Arylboronic acid SFQANAOBTUBGAH-UHFFFAOYSA-N RDSWCJZJSCGMRH-UMFDKAFQSA-N Structural feature Fluorescent reporter Colorimetric reporter
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The emission intensity response from a BODIPY-based aryl monoboronic acid was found to depend on the employed buffer at physiological pH (7.4). The structural prerequisites of the bound monosaccharides showed a clear discrimination between d-glucose and d-fructose. The different response behavior was ascribed to a major difference in the structural features of the arylboronate–monosaccharide complexes, under the employed buffered conditions. Supporting excitation measurements were found to correlate nicely with the emission experiments.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0040-4039 1873-3581
DOI:	10.1016/j.tetlet.2012.08.066