The Effect of Increased Neutrophil Lymphocyte Ratio on Mortality in Patients Operated on Due to Hip Fracture

• Published in: Curēus (Palo Alto, CA) Vol. 12; no. 1; p. e6543
• Main Authors: Atlas, Ahmet, Duran, Erdogan, Pehlivan, Başak, Pehlivan, Veli F, Erol, Mehmet K, Altay, Nuray
• Format: Journal Article
• Language: English
• Published: United States Cureus Inc 02-01-2020; Cureus
• Subjects: Anesthesia; Anesthesiology; Cardiovascular disease; Comorbidity; Fractures; Gender; Health risk assessment; Hip joint; Hospitals; Intensive care; Lymphocytes; Medical personnel; Morbidity; Mortality; Neutrophils; Older people; Patients; Surgery; Values; Womens health; mortality; intensive care; hip fracture; neutrophil lymphocyte ratio (nlr)
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.6543

Introduction In this study, we aimed to examine the effect of neutrophil-lymphocyte ratio (NLR) on mortality and morbidity in elderly patients over the age of 65 who presented to our clinic and were operated on due to hip fracture. Methods The study included patients over the age of 65 who were operated on in our hospital between January 2014 and December 2018 due to hip fracture. Those with multiple fractures and those who were operated on due to cancer-related fracture were excluded. Patients' age, gender, American Society of Anesthesiologists (ASA) score, preoperative waiting time, type of anesthesia, operation duration, amount of erythrocyte suspension used, and duration of intensive care unit (ICU) stay were recorded. The effect of increased preoperative and postoperative 5th day neutrophil-lymphocyte ratios (NLR 1 and NLR 5, respectively) on mortality and morbidity was investigated. Results We examined 132 patients operated on due to hip fracture. NLR 5 was higher among patients who were admitted to the ICU (p = 0.007) and among those who died (p = 0.007). Additionally, the rate of increase of NLR 5 was higher among patients who were admitted to the ICU (p = 0.044) and among those died (p = 0.009). Conclusion The rate of increase of NLR in the postoperative period can be used as a criterion for predicting mortality in patients who are operated on due to hip fracture.