Discordant anencephaly in a set of triplets

Discordant anencephaly in a set of triplets

A 38-year-old woman, gravida 5, para 3, with a triplet pregnancy discordant for anencephaly, is reported. The diagnosis was made prenatally by ultrasound. Autopsy of the anencephalic member revealed small adrenal glands with absent fetal cortex, and a coincidental tetralogy of Fallot. Studies of the...

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Bibliographic Details
Published in:Acta geneticae medicae et gemellologiae Vol. 33; no. 1; p. 71
Main Authors: D'Alton, M E, Newton, E R, Cetrulo, C L
Format: Journal Article
Language:English
Published: Italy 1984
Subjects:
Adult
Anencephaly - diagnosis
Anencephaly - genetics
Female
Humans
Infant, Newborn
Pregnancy
Pregnancy, Multiple
Prenatal Diagnosis
Triplets
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Description
Summary:A 38-year-old woman, gravida 5, para 3, with a triplet pregnancy discordant for anencephaly, is reported. The diagnosis was made prenatally by ultrasound. Autopsy of the anencephalic member revealed small adrenal glands with absent fetal cortex, and a coincidental tetralogy of Fallot. Studies of the histocompatible lymphocyte antigens of both parents were performed and they failed to demonstrate HLA B-27. The literature on anencephaly in triplets is summarized. The association of congenital heart disease and HLA B-27 with anencephaly is discussed.
ISSN:0001-5660
DOI:10.1017/S0001566000007522