Synchronous Uterine Metastases from Breast Cancer: Case Study and Literature Review

• Published in: Curēus (Palo Alto, CA) Vol. 9; no. 11; p. e1840
• Main Authors: Akhtar, Aisha, Ratra, Atul, Puckett, Yana, Sheikh, Abu Baker, Ronaghan, Catherine A
• Format: Journal Article
• Language: English
• Published: United States Cureus Inc 13-11-2017; Cureus
• Subjects: Abdomen; Biopsy; Bone marrow; Breast cancer; Cancer therapies; Case reports; Chemotherapy; Endometrial cancer; Family medical history; Genital cancers; Gynecology; Health sciences; Histopathology; Lymphatic system; Mammography; Metastasis; Mortality; NMR; Nuclear magnetic resonance; Obstetrics/Gynecology; Oncology; Patients; Radiation Oncology; Surgery; Ultrasonic imaging; Urogenital system; Womens health; United States > US; Texas; endometrial cancer; breast cancer; extra-genital; metastasis
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.1840

Breast cancer rarely metastasizes to the uterus. Here, we report two breast cancer patients with synchronous metastases to the uterus. Case 1 highlights a 46-year-old female with invasive ductal carcinoma who presented with a breast mass and was found to have uterine enlargement on positron emission tomography (PET) scan. Biopsy revealed a metastatic 4 mm focus of breast cancer in the background of endometrial hyperplasia. Case 2 reports a 62-year-old postmenopausal female diagnosed with lobular carcinoma of the breast following an abnormal screening mammogram. A routine pap smear necessitated further workup, revealing simultaneous endometrial and cervical metastasis. Both patients did not have any gynecologic symptoms and presented a diagnostic challenge.