Novel Quantum Molecular Resonance Energy Source for Laparoscopic Bipolar Vessel Sealer: An Experimental Study in Animal Model

This study is to evaluate a novel Quantum Molecular Resonance energy device as a laparoscopic bipolar vessel sealer. The majority of conventional bipolar energy-based vessel sealing devices utilize energy at frequencies between 300 kHz and 500 kHz. The use of such frequencies has disadvantages inclu...

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Published in:Applied sciences Vol. 12; no. 19; p. 9490
Main Authors: Bang, Seokhwan, Yu, Jiwoong, Im, Jungeun, Kwon, Soonyoung, Kim, Jongchang, Kim, Sungmin, Kim, Jung Hyun, Jeong, Byong Chang
Format: Journal Article
Language:English
Published: MDPI AG 01-10-2022
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Abstract This study is to evaluate a novel Quantum Molecular Resonance energy device as a laparoscopic bipolar vessel sealer. The majority of conventional bipolar energy-based vessel sealing devices utilize energy at frequencies between 300 kHz and 500 kHz. The use of such frequencies has disadvantages including unintended damage to surrounding tissues and excessive surgical smoke production. Here, we developed a bipolar energy source using Quantum Molecular Resonance (QMR) energy of 4–64 MHz and combined this into a laparoscopic vessel sealer. We investigate the microscopic tissue effect and surgeon’s experiences of the laparoscopic bipolar vessel sealer using a novel QMR energy source through animal experiments. QMR energy sources showed higher sealing success rates (100% vs. 66.7%) and a higher burst pressure (963 mmHg vs. 802 mmHg) of the sealed vessels compared to LigaSure™. Histological analysis showed less vessel wall injury in the QMR energy source (55.0% vs. 73.9%). In the laparoscopic setting experiments, compared to LigaSure™, QMR energy sources showed statistically significantly less smoke formation (p = 0.014), less tissue carbonization (p = 0.013), and less stickiness (p = 0.044) during sealing tissues. A novel QMR energy source for a laparoscopic bipolar vessel sealer could produce a better sealing performance and less surrounding tissue damage.
AbstractList This study is to evaluate a novel Quantum Molecular Resonance energy device as a laparoscopic bipolar vessel sealer. The majority of conventional bipolar energy-based vessel sealing devices utilize energy at frequencies between 300 kHz and 500 kHz. The use of such frequencies has disadvantages including unintended damage to surrounding tissues and excessive surgical smoke production. Here, we developed a bipolar energy source using Quantum Molecular Resonance (QMR) energy of 4–64 MHz and combined this into a laparoscopic vessel sealer. We investigate the microscopic tissue effect and surgeon’s experiences of the laparoscopic bipolar vessel sealer using a novel QMR energy source through animal experiments. QMR energy sources showed higher sealing success rates (100% vs. 66.7%) and a higher burst pressure (963 mmHg vs. 802 mmHg) of the sealed vessels compared to LigaSure™. Histological analysis showed less vessel wall injury in the QMR energy source (55.0% vs. 73.9%). In the laparoscopic setting experiments, compared to LigaSure™, QMR energy sources showed statistically significantly less smoke formation (p = 0.014), less tissue carbonization (p = 0.013), and less stickiness (p = 0.044) during sealing tissues. A novel QMR energy source for a laparoscopic bipolar vessel sealer could produce a better sealing performance and less surrounding tissue damage.
Author Jeong, Byong Chang
Kim, Jongchang
Im, Jungeun
Kwon, Soonyoung
Kim, Sungmin
Yu, Jiwoong
Bang, Seokhwan
Kim, Jung Hyun
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Cites_doi 10.3109/00016489.2012.659752
10.1016/j.jmig.2013.02.012
10.1089/end.2006.9994
10.1111/iwj.12805
10.1002/lary.20210
10.1016/j.jaad.2018.06.003
10.1002/bjs.6321
10.1371/journal.pone.0190082
10.1089/end.2008.9715
10.1016/0278-2391(87)90305-3
10.1016/S0022-5347(05)63995-X
10.1159/000101745
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References Fraccalvieri (ref_12) 2017; 14
ref_13
Chang (ref_11) 2012; 132
Landman (ref_2) 2003; 169
Georgesen (ref_3) 2018; 79
Lamberton (ref_6) 2008; 22
Lyons (ref_7) 2013; 20
Bozzola (ref_10) 2009; 119
Kalkwarf (ref_9) 1987; 45
Hubner (ref_1) 2008; 95
Cakan (ref_8) 2004; 45
Schiavon (ref_5) 2007; 39
Weld (ref_4) 2007; 21
References_xml – volume: 132
  start-page: S130
  year: 2012
  ident: ref_11
  article-title: Comparison of post-tonsillectomy pain with two different types of bipolar forceps: Low temperature quantum molecular resonance device versus high temperature conventional electrocautery
  publication-title: Acta Otolaryngol.
  doi: 10.3109/00016489.2012.659752
  contributor:
    fullname: Chang
– volume: 20
  start-page: 301
  year: 2013
  ident: ref_7
  article-title: Laparoscopic vessel sealing technologies
  publication-title: J. Minim. Invasive Gynecol.
  doi: 10.1016/j.jmig.2013.02.012
  contributor:
    fullname: Lyons
– volume: 21
  start-page: 347
  year: 2007
  ident: ref_4
  article-title: Analysis of surgical smoke produced by various energy-based instruments and effect on laparoscopic visibility
  publication-title: J. Endourol.
  doi: 10.1089/end.2006.9994
  contributor:
    fullname: Weld
– volume: 14
  start-page: 1313
  year: 2017
  ident: ref_12
  article-title: Quantum molecular resonance technology in hard-to-heal extremity wounds: Histological and clinical results
  publication-title: Int. Wound J.
  doi: 10.1111/iwj.12805
  contributor:
    fullname: Fraccalvieri
– volume: 119
  start-page: 1897
  year: 2009
  ident: ref_10
  article-title: Molecular resonance vs. coblation tonsillectomy in children
  publication-title: Laryngoscope
  doi: 10.1002/lary.20210
  contributor:
    fullname: Bozzola
– volume: 79
  start-page: 746
  year: 2018
  ident: ref_3
  article-title: Surgical smoke: Risk assessment and mitigation strategies
  publication-title: J. Am. Acad. Dermatol.
  doi: 10.1016/j.jaad.2018.06.003
  contributor:
    fullname: Georgesen
– volume: 95
  start-page: 1098
  year: 2008
  ident: ref_1
  article-title: Prospective randomized study of monopolar scissors, bipolar vessel sealer and ultrasonic shears in laparoscopic colorectal surgery
  publication-title: Br. J. Surg.
  doi: 10.1002/bjs.6321
  contributor:
    fullname: Hubner
– volume: 45
  start-page: 63
  year: 2004
  ident: ref_8
  article-title: The histological effect of harmonic scalpel and electrocautery in lung resections. An experimental study in a rat model
  publication-title: J. Cardiovasc. Surg.
  contributor:
    fullname: Cakan
– ident: ref_13
  doi: 10.1371/journal.pone.0190082
– volume: 22
  start-page: 2307
  year: 2008
  ident: ref_6
  article-title: Prospective comparison of four laparoscopic vessel ligation devices
  publication-title: J. Endourol.
  doi: 10.1089/end.2008.9715
  contributor:
    fullname: Lamberton
– volume: 45
  start-page: 671
  year: 1987
  ident: ref_9
  article-title: Histologic evaluation of gingival response to an electrosurgical blade
  publication-title: J. Oral Maxillofac. Surg.
  doi: 10.1016/0278-2391(87)90305-3
  contributor:
    fullname: Kalkwarf
– volume: 169
  start-page: 697
  year: 2003
  ident: ref_2
  article-title: Evaluation of a vessel sealing system, bipolar electrosurgery, harmonic scalpel, titanium clips, endoscopic gastrointestinal anastomosis vascular staples and sutures for arterial and venous ligation in a porcine model
  publication-title: J. Urol.
  doi: 10.1016/S0022-5347(05)63995-X
  contributor:
    fullname: Landman
– volume: 39
  start-page: 222
  year: 2007
  ident: ref_5
  article-title: Favorable tissue effects of quantum molecular resonance device (Vesalius) compared with standard electrocautery. A novel paradigm in lung surgery
  publication-title: Eur. Surg. Res.
  doi: 10.1159/000101745
  contributor:
    fullname: Schiavon
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SubjectTerms laparoscopic surgery
QMR
quantum molecular resonance
surgical energy device
surgical smoke
vessel sealing technologies
Title Novel Quantum Molecular Resonance Energy Source for Laparoscopic Bipolar Vessel Sealer: An Experimental Study in Animal Model
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