Target cell - substratum interaction. I. Effect of primed lymphocytes on a rat mammary adenocarcinoma tumor cell line

The differential effects of normal and immunologically primed lymphocytes on the adherence of trypsinized rat mammary adenocarcinoma tumor cells (DMBA"8) to their substratum are described, utilizing both allogeneically and syngeneically primed lymphoid cells as effectors. This observation may i...

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Bibliographic Details
Published in:	Immunological communications Vol. 7; no. 3; p. 337
Main Authors:	David, G S, Wiglesworgh, C M
Format:	Journal Article
Language:	English
Published:	United States 1978
Subjects:	Adenocarcinoma - immunology Animals Antigens, Neoplasm Cell Adhesion Cell Line Cytotoxicity Tests, Immunologic Epitopes Female Immunity, Cellular In Vitro Techniques Lymphocyte Activation Lymphocytes - immunology Mammary Neoplasms, Experimental - immunology Rats Rats, Inbred BN Rats, Inbred F344 Trypsin - pharmacology
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Summary:	The differential effects of normal and immunologically primed lymphocytes on the adherence of trypsinized rat mammary adenocarcinoma tumor cells (DMBA"8) to their substratum are described, utilizing both allogeneically and syngeneically primed lymphoid cells as effectors. This observation may illustrate an important immunological phenomenon, and may result in a simplified assay procedure for the detection of cell-mediated immunity.
ISSN:	0090-0877
DOI:	10.3109/08820137809025477