Versatile Palladium/Triphosphane System for Direct Arylation of Heteroarenes with Chloroarenes at Low Catalyst Loading

Versatile Palladium/Triphosphane System for Direct Arylation of Heteroarenes with Chloroarenes at Low Catalyst Loading

Put a ring on it: The use of an air‐stable, robust palladium/tridentate phosphane catalyst in direct CH and CCl activation reactions is reported (see scheme; DMAc=N,N‐dimethylacetamide, TBAB=tetra‐n‐butylammonium bromide). Electron‐rich, electron‐poor, and polysubstituted furans (X=O), thiophenes...

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Bibliographic Details
Published in:Angewandte Chemie (International ed.) Vol. 49; no. 37; pp. 6650 - 6654
Main Authors: Roy, David, Mom, Sophal, Beaupérin, Matthieu, Doucet, Henri, Hierso, Jean-Cyrille
Format: Journal Article
Language:English
Published: Weinheim Wiley-VCH Verlag 03-09-2010
WILEY-VCH Verlag
WILEY‐VCH Verlag
Subjects:
CH activation
direct arylation
heterocycles
palladium
synthetic methods
Online Access:Get full text
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Summary:Put a ring on it: The use of an air‐stable, robust palladium/tridentate phosphane catalyst in direct CH and CCl activation reactions is reported (see scheme; DMAc=N,N‐dimethylacetamide, TBAB=tetra‐n‐butylammonium bromide). Electron‐rich, electron‐poor, and polysubstituted furans (X=O), thiophenes (X=S), pyrroles (X=NR5), and thiazoles were arylated with chloroarenes in the presence of the catalyst.
Bibliography:http://dx.doi.org/10.1002/anie.201002987
ark:/67375/WNG-B45QGT2J-R
CNRS
istex:9003297768D1670A030DCDEBC9B8E4BE295746CA
Support provided from the ANR program for Sustainable Chemistry Development (ANR-09-CP2D-03 CAMELOT), the Région Bourgogne (PARI SMT8), Rennes Métropole, and the CNRS (3MIM program P4 on Heterochemistry), is gratefully acknowledged.
ANR program - No. ANR-09-CP2D-03 CAMELOT
Rennes Métropole
ArticleID:ANIE201002987
Région Bourgogne
Support provided from the ANR program for Sustainable Chemistry Development (ANR‐09‐CP2D‐03 CAMELOT), the Région Bourgogne (PARI SMT8), Rennes Métropole, and the CNRS (3MIM program P4 on Heterochemistry), is gratefully acknowledged.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201002987