Isoquinolinium bromochromate: An efficient and stable reagent for bromination of hydroxylated aromatic compounds and oxidation of alcohols

• Published in: Chinese chemical letters Vol. 20; no. 3; pp. 256 - 260
• Main Authors: Khansole, Sandeep V., Patwari, Shivaji B., Vibhute, Archana Y., Vibhute, Yeshwant B.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01-03-2009; PG. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded 431605, India
• Subjects: Alcohols; Bromination; Hydroxylated aromatics; Isoquinolinium bromochromate; Oxidation; Isoquinolinium bromochromate; Oxidation; Bromination; Hydroxylated aromatics; Alcohols
• ISSN: 1001-8417; 1878-5964
• DOI: 10.1016/j.cclet.2008.11.015

The new chromium (VI) oxidizing reagent isoquinolinium bromochromate (IQBC) was prepared and characterized. The IQBC has been found to be stable and an efficient solid reagent which can be easily prepared in good yield. It act as an efficient brominating reagent for hydroxylated aromatic compounds as well as good oxidizing reagent for the conversion of alcohols to carbonyl compounds in good to excellent yield. The synthesized isoquinolinium bromochromate is more ideal reagent, with number of specification including: higher yield, mild conditions and easy preparation. The results obtained with isoquinolinium bromochromate are satisfactory and suggest that the reagent has few advantages over the existing chromium (VI) reagents.